Single-Cell Transcriptomic Analysis of Dental Pulp and Periodontal Ligament Stem Cells

Y Yang, T Alves, MZ Miao, YC Wu, G Li… - Journal of Dental …, 2024 - journals.sagepub.com
The regeneration of periodontal, periapical, and pulpal tissues is a complex process
requiring the direct involvement of cells derived from pluripotent stem cells in the periodontal …

Proteome of human stem cells from periodontal ligament and dental pulp

E Eleuterio, O Trubiani, M Sulpizio, F Di Giuseppe… - PLoS …, 2013 - journals.plos.org
Background Many adult tissues contain a population of stem cells with the ability to
regenerate structures similar to the microenvironments from which they are derived in vivo …

Single-cell RNA sequencing analysis of human dental pulp stem cell and human periodontal ligament stem cell

S Lee, D Chen, M Park, S Kim, YJ Choi, SJ Moon… - Journal of …, 2022 - Elsevier
Introduction Many studies have investigated the transcriptome profiles of dental stem cells
for regenerative medicine. However, such studies use bulk RNA and do not consider cell …

Periodontal ligament stem cells: current knowledge and future perspectives

O Trubiani, J Pizzicannella, S Caputi… - Stem cells and …, 2019 - liebertpub.com
Teeth represent a fascinating area of study in regenerative medicine, because of their
unique and complex developmental origin. Several types of mesenchymal stem cells …

Dental pulp stem cells: from discovery to clinical application

B Sui, D Wu, L Xiang, Y Fu, X Kou, S Shi - Journal of endodontics, 2020 - Elsevier
Postnatal stem cells critically maintain tissue homeostasis and possess immense potential
for tissue regeneration. These stem cells in the orofacial system were not identified until …

Comparative analysis of dental pulp and periodontal stem cells: differences in morphology, functionality, osteogenic differentiation and proteome

AV Kotova, AA Lobov, JA Dombrovskaya… - Biomedicines, 2021 - mdpi.com
Dental stem cells are heterogeneous in their properties. Despite their common origin from
neural crest stem cells, they have different functional capacities and biological functions due …

Human dental pulp stem cells (hDPSCs): isolation, enrichment and comparative differentiation of two sub-populations

A Pisciotta, G Carnevale, S Meloni, M Riccio… - BMC developmental …, 2015 - Springer
Background Human dental pulp represents a suitable alternative source of stem cells for the
purpose of cell-based therapies in regenerative medicine, because it is relatively easy to …

Molecular biological comparison of dental pulp-and apical papilla-derived stem cells

M Smeda, KM Galler, M Woelflick, A Rosendahl… - International Journal of …, 2022 - mdpi.com
Both the dental pulp and the apical papilla represent a promising source of mesenchymal
stem cells for regenerative endodontic protocols. The aim of this study was to outline …

Periodontal ligament stem cells: an overview

A Acharya, S Shetty, V Deshmukh - Journal of Oral Biosciences, 2010 - jstage.jst.go.jp
Adult postnatal stem cells are multipotent and can be experimentally induced to differentiate
into various specialized cell lineages. This has generated considerable interest in the arena …

Single-cell characterization of monolayer cultured human dental pulp stem cells with enhanced differentiation capacity

Y Cui, W Ji, Y Gao, Y Xiao, H Liu, Z Chen - International Journal of Oral …, 2021 - nature.com
Human dental pulp stem cells (hDPSCs) are easily obtained multipotent cells, however, their
potential value in regenerative medicine is hindered by the phenotypic and functional …