Frontotemporal lobar degeneration (FTLD) has been associated with toxic intracellular
aggregates of hyperphosphorylated tau (FTLD‐tau). Moreover, genetic studies identified …

Both Alzheimer's disease (AD) and almost every second case of frontotemporal lobar
degeneration (FTLD) are characterized by the deposition of hyperphosphorylated forms of …

Frontotemporal lobar degeneration (FTLD) is a group of heterogeneous neurodegenerative
diseases which includes tauopathies. In the central nervous system (CNS) tau is the major …

The tauopathies constitute a group of diseases that have Tau inclusions in neurons or glia
as their common denominator. In this review, we describe the biochemical and histological …

The frontotemporal tauopathies all deposit abnormal tau protein aggregates, but often of
only certain isoforms and in distinguishing pathologies of five main types (neuronal Pick …

The microtubule-associated protein (MAP) tau plays a critical role in the pathogenesis of
Alzheimer's disease (AD) and several related disorders collectively known as tauopathies …

Tau, a microtubule-associated protein, is the main component of the intracellular filamentous
inclusions that are involved in neurodegenerative diseases known as tauopathies, including …

Tau is a microtubule-associated binding protein in the nervous system that is known for its
role in stabilizing microtubules throughout the nerve cell. It accumulates as β-sheet-rich …

Tau is a multifunctional protein that was originally identified as a microtubule‐associated
protein. In patients diagnosed with frontotemporal dementia and parkinsonism linked to …

Tauopathies are a class of neurodegenerative disorders characterized by neuronal and/or
glial inclusions composed of the microtubule-binding protein, tau. Several lines of evidence …