Efficacy and safety of anlotinib in the treatment of small cell lung cancer: A real-world observation study

J Yuan, F Cheng, G Xiao, X Wang, H Fan - Frontiers in Oncology, 2022 - frontiersin.org
Aims This study aimed to observe the efficacy and safety of anlotinib in the treatment of small
cell lung cancer (SCLC) in the real world, as first-line maintenance therapy, second-line, and …

Effectiveness and safety of anlotinib monotherapy for patients with extensive-stage small-cell lung cancer who progressed to chemotherapy: a real-world exploratory …

Y Li, Z Sun, W Sun, H Wang… - Clinical Medicine Insights …, 2022 - journals.sagepub.com
Background: Anlotinib demonstrated promising efficacy for patients with extensive-stage
small-cell lung cancer (ES-SCLC) in clinical trials. However, the real-world evidence of …

Response to first‐line treatment predicts progression‐free survival benefit of small‐cell lung cancer patients treated with anlotinib

B Qin, L Xin, Q Hou, B Yang, J Zhang, X Qi… - Cancer …, 2021 - Wiley Online Library
Background Anlotinib significantly extended progression‐free survival (PFS) and overall
survival (OS) in small‐cell lung cancer (SCLC) as third or later line treatment. Methods In this …

Anlotinib vs placebo as third-or further-line treatment for patients with small cell lung cancer: a randomised, double-blind, placebo-controlled Phase 2 study

Y Cheng, Q Wang, K Li, J Shi, Y Liu, L Wu… - British Journal of …, 2021 - nature.com
Background This study aimed to evaluate the efficacy and safety of anlotinib as a third-line
and subsequent treatment for patients with small cell lung cancer (SCLC). Methods We …

Real-world efficacy and safety of anlotinib as third-or further-line treatment in refractory small cell lung cancer

X Gao, L Peng, L Zhang, K Huang, C Yi, B Li… - Journal of Cancer …, 2021 - Springer
Purpose As a novel antiangiogenic multi-target tyrosine kinase inhibitor recently approved in
China, anlotinib has exhibited promising anticancer efficacy and acceptable safety profile in …

[PDF][PDF] The efficacy and safety of anlotinib in extensive-stage small cell lung cancer: a multicenter real-world study

HR Zheng, AM Jiang, H Gao, N Liu… - Cancer Management …, 2022 - Taylor & Francis
Purpose Anlotinib, an antiangiogenic multi-target tyrosine kinase inhibitor (TKI), has shown
favorable anticancer efficacy and acceptable safety in treating extensive-stage small cell …

Safety and efficacy of anlotinib in combination with standard chemotherapy as first-line treatment for extensive-stage small cell lung cancer: a multi-center, prospective …

W Zhang, P Deng, T Kong, B Zhang, F Qian, Y Dong… - Lung Cancer, 2022 - Elsevier
Introduction Extensive stage small cell lung cancer (ES-SCLC) is associated with poor
prognosis. Recently, anlotinib has demonstrated significant clinical activity as a third-line or …

P48. 11 Anlotinib Versus Chemotherapy as a Third-Line or Further Treatment for Advanced Small Cell Lung Cancer

Y Wang, X Ling, S Cao, J Li, Y Zhou, W Nie… - Journal of Thoracic …, 2021 - jto.org
Methods This study included 55 advanced SCLC patients (n= 28 for anlotinib group and n=
27 for chemotherapy group) from Shanghai Chest hospital between January 2017 and …

Anlotinib-containing regimen for advanced small-cell lung cancer: A protocol of meta-analysis

G Yu, Q Cai, X Xu, Y Shen, K Xu - Plos one, 2021 - journals.plos.org
Background Small cell lung cancer (SCLC) is a highly malignant lung cancer with a very
poor prognosis. Clinical treatment options for SCLC are still limited, especially for patients …

The efficacy and safety of anlotinib combined with platinum-etoposide chemotherapy as first-line treatment for extensive-stage small cell lung cancer: A Chinese …

HR Zheng, AM Jiang, H Gao, N Liu, XQ Zheng… - Frontiers in …, 2022 - frontiersin.org
Background Patients with extensive-stage small-cell lung cancer (ES-SCLC) have high
recurrence rates and bleak prognosis. This multicenter real-world study aimed to explore the …