Self microemulsifying drug delivery system of lurasidone hydrochloride for enhanced oral bioavailability by lymphatic targeting: in vitro, Caco-2 cell line and in vivo …
The global aim of this research was to develop and evaluate self-microemulsifying drug
delivery system (SMEDDS) to improve oral bioavailability of Lurasidone Hydrochloride (LH) …
delivery system (SMEDDS) to improve oral bioavailability of Lurasidone Hydrochloride (LH) …
Oral absorption and lymphatic transport of baicalein following drug–phospholipid complex incorporation in self-microemulsifying drug delivery systems
H Liao, Y Gao, C Lian, Y Zhang, B Wang… - International journal …, 2019 - Taylor & Francis
Purpose The aims of this study were to prepare a baicalein self-microemulsion with
baicalein-phospholipid complex as the intermediate (BAPC-SMEDDS) and to compare its …
baicalein-phospholipid complex as the intermediate (BAPC-SMEDDS) and to compare its …
Formulation and characterization of lipid-based drug delivery system of raloxifene-microemulsion and self-microemulsifying drug delivery system
Background: Raloxifene, a second-generation selective estrogen receptor modulator
(SERM) used to prevent osteoporosis in postmenopausal women is administered orally in …
(SERM) used to prevent osteoporosis in postmenopausal women is administered orally in …
Novel Drug Delivery Approach via Self-Microemulsifying Drug Delivery System for Enhancing Oral Bioavailability of Asenapine Maleate: Optimization, Characterization, Cell …
Asenapine maleate (AM)-loaded self-microemulsifying drug delivery system (AM-SMEDDS)
was prepared to increase its oral bioavailability. AM-SMEDDS was developed using Capryol …
was prepared to increase its oral bioavailability. AM-SMEDDS was developed using Capryol …
Development and pharmacokinetic evaluation of industrially viable self-microemulsifying drug delivery systems (SMEDDS) for terbinafine
A Baheti, S Srivastava, D Sahoo… - Current drug …, 2016 - ingentaconnect.com
Objective: The aim of this study was to develop a formulation for lymphatic uptake with
enhanced solubility of antifungal drug, terbinafine by use of self-microemulsifying drug …
enhanced solubility of antifungal drug, terbinafine by use of self-microemulsifying drug …
[HTML][HTML] Enhanced intestinal lymphatic absorption of saquinavir through supersaturated self-microemulsifying drug delivery systems
K Jo, H Kim, P Khadka, T Jang, SJ Kim… - Asian Journal of …, 2020 - Elsevier
The therapeutic potential of saquinavir, a specific inhibitor of human immunodeficiency virus
(HIV)-1 and HIV-2 protease enzymes, has been largely limited because of a low solubility …
(HIV)-1 and HIV-2 protease enzymes, has been largely limited because of a low solubility …
Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability
Poor aqueous solubility and dissolution limit the oral bioavailability of Biopharmaceutics
Classification System (BCS) class II drugs. In this study, we aimed to improve the aqueous …
Classification System (BCS) class II drugs. In this study, we aimed to improve the aqueous …
Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation
X Sha, J Wu, Y Chen, X Fang - International Journal of …, 2012 - Taylor & Francis
The objective of our investigation was to design a self-microemulsifying drug-delivery
system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of …
system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of …
Self microemulsifying particles of loratadine for improved oral bioavailability: preparation, characterization and in vivo evaluation
KV Madhav, V Kishan - Journal of Pharmaceutical Investigation, 2018 - Springer
The objective was to study the phase behavior of different formulations, to identify the micro
emulsion area and to prepare solid SMEDDS particles (SSMED) of loratadine (LOR) for …
emulsion area and to prepare solid SMEDDS particles (SSMED) of loratadine (LOR) for …
Dissolution evaluation in vitro and bioavailability in vivo of self-microemulsifying drug delivery systems for pH-sensitive drug loratadine
H Li, Y Tan, L Yang, L Gao, T Wang… - Journal of …, 2015 - Taylor & Francis
The aim of this study was to improve the oral absorption of loratadine, a pH-sensitive drug,
by self-microemulsifying drug delivery systems (SMEDDSs). The optimal SMEDDS was …
by self-microemulsifying drug delivery systems (SMEDDSs). The optimal SMEDDS was …