Benefit with first-line ICIs in mesothelioma

D Romero - Nature Reviews Clinical Oncology, 2021 - nature.com
The combination of platinum agents with pemetrexed has been the standard-of-care
treatment for unresectable malignant pleural mesothelioma (MPM), although outcomes …

Updates in Management of Malignant Pleural Mesothelioma

A John, H O'Sullivan, S Popat - Current Treatment Options in Oncology, 2023 - Springer
Opinion statement Malignant pleural mesothelioma (MPM) is an aggressive asbestos-
associated thoracic malignancy that is usually incurable. As demonstrated in the landmark …

Current management and future perspective in pleural mesothelioma

R Shah, LV Klotz, J Glade - Cancers, 2022 - mdpi.com
Simple Summary Platin-based chemotherapy with pemetrexed has been the backbone of
meaningful treatment in pleural mesothelioma for the last 16 years, alongside vinorelbine …

[HTML][HTML] Biomarkers in malignant pleural mesothelioma: current status and future directions

T Ahmadzada, G Reid, S Kao - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
Ahmadzada et al. Biomarkers in mesothelioma who are candidates for surgery undergo
either extra-pleural pneumonectomy (EPP), which involves macroscopic removal of the …

Brief report: Meta-analysis on chemotherapy and PD-(L) 1 blockade combination as first-line treatment for unresectable pleural mesothelioma.

M Tagliamento, M Di Maio, J Remon… - Journal of Thoracic …, 2023 - europepmc.org
Background Dual immune checkpoint blockers (ICBs) regimen represents a standard first-
line therapy in unresectable pleural mesothelioma (PM). Novel combination strategies …

Cetuximab plus platinum-based chemotherapy in patients with malignant pleural mesothelioma: A single arm phase II trial.

A De Paepe, KY Vermaelen, R Cornelissen… - 2017 - ascopubs.org
e20030 Background: Cetuximab is a chimeric monoclonal antibody targeting the epidermal
growth factor receptor (EGFR). Previous studies suggested that cetuximab enhances …

An update on emerging therapeutic options for malignant pleural mesothelioma

A Davis, H Ke, S Kao, N Pavlakis - Lung Cancer: Targets and …, 2022 - Taylor & Francis
The treatment paradigm for malignant pleural mesothelioma (MPM) has changed little in the
last 18 years. Radical intent treatment, consisting of surgical resection, radiotherapy and …

Novel therapies in phase II and III trials for malignant pleural mesothelioma

MG Zauderer, LM Krug - Journal of the National Comprehensive Cancer …, 2012 - jnccn.org
Mesothelioma is a rare malignancy of the pleura with limited therapeutic options. Despite the
desperate need to develop better treatment for this disease, the rarity of the tumor type …

The evolving therapeutic landscape for malignant pleural mesothelioma

ND Perera, AS Mansfield - Current oncology reports, 2022 - Springer
Abstract Purpose of Review For patients with malignant pleural mesothelioma, prognosis is
poor with extremely low 5-year survival rates and limited therapeutic options. Here, we …

Malignant pleural mesothelioma: new guidelines make us stronger for defeating this disease

J Remon, LEL Hendriks, P Bironzo - Annals of Oncology, 2022 - annalsofoncology.org
Malignant pleural mesothelioma (MPM) remains a rare thoracic malignancy with an
incidence in Europe of 1.83 cases per 100 000 individuals annually. 1 Asbestos exposure is …