Unlike T cells that recognize digested peptides, B cells recognize their cognate antigen in its
native form. The B cell receptor used in recognition can also be secreted to bind to antigens …

B cell recognition of membrane-bound antigens leads to the formation of an immunological
synapse and efficient B cell activation. Ongoing research has been directed towards …

Binding of antigen to B‐cell antigen receptor (BCR) leads to antigen internalization and
presentation to T cells, a critical process in the initiation of the humoral immune response …

B lymphocytes are regarded as professional antigen-presenting cells (APCs) despite their
primary role in humoral immunity. Over the last two decades, studies designed to define the …

Several characteristics confer on B cells the ability to present antigen efficiently:(1) they can
find T cells in secondary lymphoid organs shortly after antigen entrance,(2) BCR-mediated …

Mature B lymphocytes (B cells) recognize antigens using their B cell receptor (BCR) and are
activated to become antibody-producing cells. In addition, and integral to the development of …

Publisher Summary This chapter reviews the evidence in favor of the concept that B cells
can serve as antigen-presenting accessory cells to T cells of the helper/inducer subset as …

In the 25 years since it was first indicated that lymphocyte subpopulations must interact
during the generation of a humoral immune response, there has been an explosion of data …

The binding of antigen to the B‐cell receptor (BCR) induces BCR clustering and signaling
cascades that lead to the activation of a variety of genes associated with B‐cell activation …

B cells are key components of the adaptive immune response. Their differentiation into
either specific memory B cells or antibody-secreting plasma cells is a consequence of …