As the infectious agent causing human adult T-cell leukemia (ATL), the human T-cell
leukemia virus type 1 (HTLV-1) virus spreads in vivo primarily by cell-to-cell transmission …

Transforming growth factor β (TGFβ) regulates essential cellular functions such as cellular
proliferation, differentiation, and apo pto sis. The Bcl-2 family of proteins has been implicated …

Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a
causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory …

Human T-cell leukemia virus type 1 (HTLV-1) is an etiological agent of several inflammatory
diseases and a T-cell malignancy, adult T-cell leukemia (ATL). HTLV-1 bZIP factor (HBZ) is …

Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL)
and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in …

Human T-cell leukemia virus type 1 (HTLV-1) infects CD4+ T cells and induces proliferation
of infected cells in vivo, which leads to the onset of adult T-cell leukemia (ATL) in some …

Human T-cell leukemia virus type 1 (HTLV-1) causes both a neoplastic disease and
inflammatory diseases, including HTLV-1-associated myelopathy/tropical spastic …

Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of
CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 …

Proliferation, differentiation, and survival of hematopoietic cells are regulated by cytokines,
acting through specific receptors. FLT3 ligand (FL) is one of the most important cytokines for …

The transcription factor forkhead box O 3A (FOXO3A) is a tumor suppressor that promotes
cell cycle arrest and apoptosis. Piperlongumine (PL), a plant alkaloid, is known to selectively …