Elevated expression of miR-146, miR-139 and miR-340 involved in regulating Th1/Th2 balance with acute exposure of fine particulate matter in mice

T Hou, J Liao, C Zhang, C Sun, X Li, G Wang - International …, 2018 - Elsevier
Airborne fine particulate matter (PM2. 5) is detrimental to human health, and frequently leads
to a variety of lung diseases. Recently, IARC conclude that particulate matter is carcinogenic …

NF-κB-regulation of miR-155, via SOCS1/STAT3, is involved in the PM2. 5-accelerated cell cycle and proliferation of human bronchial epithelial cells

T Xiao, M Ling, H Xu, F Luo, J Xue, C Chen… - Toxicology and Applied …, 2019 - Elsevier
Air pollution, especially fine particulate matter (PM 2.5, particles< 2.5 μm in size), induces
adverse health effects on the respiratory system. Uncontrolled proliferation of bronchial …

[HTML][HTML] microRNA-802/Rnd3 pathway imposes on carcinogenesis and metastasis of fine particulate matter exposure

X Li, N Gao, H Sun, R Lu, H Yang, C Zhang, Q Meng… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recent studies have linked ambient fine particulate matter (PM 2.5) to increased lung cancer
mortality and morbidity. However, the underlying mechanism causing the adverse effects of …

MiR‐146a regulates PM1‐induced inflammation via NF‐κB signaling pathway in BEAS‐2B cells

L Liu, C Wan, W Zhang, L Guan, G Tian… - Environmental …, 2018 - Wiley Online Library
Exposure to particulate matter (PM) leads to kinds of cardiopulmonary diseases, such as
asthma, COPD, arrhythmias, lung cancer, etc., which are related to PM‐induced …

MicroRNA-382-5p is involved in pulmonary inflammation induced by fine particulate matter exposure

X Zhang, Y Zhang, Q Meng, H Sun, S Wu, J Xu… - Environmental …, 2020 - Elsevier
Exposure to atmospheric particulate matter (PM) has been related to the increasing
incidence and mortality of pulmonary diseases, where microRNAs (miRNAs) play significant …

Downregulated miR-129-5p expression inhibits rat pulmonary fibrosis by upregulating STAT1 gene expression in macrophages

Q Qian, Q Ma, B Wang, Q Qian, C Zhao, F Feng… - International …, 2022 - Elsevier
Objective This study investigated the mechanism by which microRNA-129-5p (miR-129-5p)
in macrophages affects pulmonary fibrosis in rats by regulating the expression of the signal …

A novel inhibitory role of microRNA‐224 in particulate matter 2.5‐induced asthmatic mice by inhibiting TLR2

P Li, J Wang, F Guo, B Zheng… - Journal of cellular and …, 2020 - Wiley Online Library
Epidemiological studies have shown that elevated concentrations of particulate matter 2.5
(PM2. 5) correlate with increased incidence of asthma. Studies have highlighted the …

microRNA-146a-5p negatively modulates PM2. 5 caused inflammation in THP-1 cells via autophagy process

Y Shang, Q Liu, L Wang, X Qiu, Y Chen, J An - Environmental pollution, 2021 - Elsevier
Ambient fine particulate matter (PM 2.5) can change the expression profile of microRNAs
(miRs), which may play important roles in mediating inflammatory responses. The present …

[HTML][HTML] Upregulation of miRNA‑140‑5p inhibits inflammatory cytokines in acute lung injury through the MyD88/NF‑κB signaling pathway by targeting TLR4

Y Yang, D Liu, Y Xi, J Li, B Liu… - Experimental and …, 2018 - spandidos-publications.com
The present study was designed to determine the effect of miR‑140‑5p on acute lung injury
(ALI) and the associated inflammation induced. As a result, miR‑140‑5p expression in mice …

[HTML][HTML] PM2. 5 upregulates MicroRNA-146a-3p and induces M1 polarization in RAW264. 7 cells by targeting Sirtuin1

Y Zhong, J Liao, Y Hu, Y Wang, C Sun… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Background: Fine particulate matter (PM 2.5) exposure is proved to be associated with
illnesses, but the mechanism is not clear. Potential effects of PM 2.5 on innate immunity …