Expression of an engineered acidic-subunit 11S globulin of amaranth carrying the antihypertensive peptides VY, in transgenic tomato fruits

LJ Germán-Báez, A Cruz-Mendívil… - Plant Cell, Tissue and …, 2014 - Springer
The acidic-subunit of amarantin, main seed storage protein of Amaranthus
hypochondriacus, carrying four antihypertensive biopeptides Val-Tyr was expressed in the …

Expression of the acidic-subunit of amarantin, carrying the antihypertensive biopeptides VY, in cell suspension cultures of Nicotiana tabacum NT1

DU Santos-Ballardo, LJ Germán-Báez… - Plant Cell, Tissue and …, 2013 - Springer
A modified version of amarantin, main seed storage protein of Amaranthus
hypochondriacus, carrying four antihypertensive biopeptides Val-Tyr into the acidic-subunit …

Antihypertensive activity of AMC3, an engineered 11S amaranth globulin expressed in Escherichia coli, in spontaneously hypertensive rats

S Medina-Godoy, SK Rodríguez-Yáñez… - Journal of Functional …, 2013 - Elsevier
The acidic-subunit of 11S seed storage globulin of Amaranthus hypochondriacus was
recently modified by the incorporation of antihypertensive biopeptides: four units of Val–Tyr …

Amaranth seed protein hydrolysates have in vivo and in vitro antihypertensive activity

M Fritz, B Vecchi, G Rinaldi, MC Añón - Food Chemistry, 2011 - Elsevier
The objective of this work was to study the hydrolytic release of encrypted peptides with
antihypertensive activity from storage proteins of Amaranthus mantegazzianus, as …

Amaranth as a source of antihypertensive peptides

AE Nardo, S Suárez, AV Quiroga… - Frontiers in Plant Science, 2020 - frontiersin.org
Amaranth is an ancestral crop used by pre-Columbian cultures for 6000 to 8000 years. Its
grains have a relevant chemical composition not only from a nutritional point of view but also …

[HTML][HTML] Expression, purification and thermal stability evaluation of an engineered amaranth protein expressed in Escherichia coli

JI Morales-Camacho, O Paredes-López… - Electronic Journal of …, 2016 - SciELO Chile
Background: The acidic subunit of amarantin (AAC)-the predominant amaranth seed storage
protein-has functional potential and its third variable region (VR) has been modified with …

Modification of the amaranth 11S globulin storage protein to produce an inhibitory peptide of the angiotensin I converting enzyme, and its expression in Escherichia …

S Luna-Suárez, S Medina-Godoy… - Journal of …, 2010 - Elsevier
Amarantin is the predominant seed storage protein from amaranth. It shows a high content of
essential amino acids, making this protein important from a nutritional viewpoint. The protein …

[HTML][HTML] The insertion of bioactive peptides at the C-terminal end of an 11S globulin changes the structural stability and improves the antihypertensive activity

E Espinosa-Hernández, JI Morales-Camacho… - Electronic Journal of …, 2019 - Elsevier
Background The 11S globulin from amaranth is the most abundant storage protein in mature
seeds and is well recognized for its nutritional value. We used this globulin to engineer a …

Expression and characterization of the acidic subunit from 11S amaranth seed protein

S Luna‐Suárez, S Medina‐Godoy… - Biotechnology …, 2008 - Wiley Online Library
Amarantin acidic subunit has the potential to be employed as a functional and a
nutraceutical protein. To evaluate both possibilities this protein was produced in …

Action of amaranth peptides on the cardiovascular system

MC Añón, AV Quiroga, AA Scilingo… - Native Crops in Latin …, 2022 - taylorfrancis.com
The amaranth grain storage proteins contain a series of encrypted amino acid sequences
that exhibit different physiological activities when they are released. These include …