The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells

VS Grytting, P Chand, M Låg, J Øvrevik… - Particle and Fibre …, 2022 - Springer
Background People are exposed to ambient particulate matter (PM) from multiple sources
simultaneously in both environmental and occupational settings. However, combinatory …

Inflammation‐Related Effects of Diesel Engine Exhaust Particles: Studies on Lung Cells In Vitro

PE Schwarze, AI Totlandsdal, M Låg… - BioMed research …, 2013 - Wiley Online Library
Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in
humans. In the development of these effects inflammation is regarded as a key process …

Differential proinflammatory responses induced by diesel exhaust particles with contrasting PAH and metal content

AI Totlandsdal, M Låg, E Lilleaas… - Environmental …, 2015 - Wiley Online Library
Exposure to diesel engine exhaust particles (DEPs), representing a complex and variable
mixture of components, has been linked with cellular production and release of several …

Diesel exhaust particles induce CYP1A1 and pro-inflammatory responses via differential pathways in human bronchial epithelial cells

AI Totlandsdal, FR Cassee, P Schwarze… - Particle and fibre …, 2010 - Springer
Background Exposure to diesel engine exhaust particles (DEPs) has been associated with
several adverse health outcomes in which inflammation seems to play a key role. DEPs …

Biological effects of atmospheric particles on human bronchial epithelial cells. Comparison with diesel exhaust particles

A Baulig, M Sourdeval, M Meyer, F Marano… - Toxicology in vitro, 2003 - Elsevier
Epidemiological studies have associated the increase of respiratory disorders with high
levels of ambient particulate matter (PM) levels although the underlying biological …

[HTML][HTML] Effects of diesel exhaust particles on human lung epithelial cells: an in vitro study

G Mazzarella, F Ferraraccio, MV Prati, S Annunziata… - Respiratory …, 2007 - Elsevier
Atmospheric particulate matter (PM), an ingredient of urban pollution matter, is a mixture of
solid and liquid particles differing in origin, dimension and composition. There is big concern …

Biological responses to diesel exhaust particles (DEPs) depend on the physicochemical properties of the DEPs

EJ Park, J Roh, MS Kang, SN Kim, Y Kim, S Choi - PloS one, 2011 - journals.plos.org
Diesel exhaust particles (DEPs) are the main components of ambient particulate materials,
including polyaromatic hydrocarbons (PAHs), n-PAHs, heavy metals, and gaseous …

Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

J Ji, S Upadhyay, X Xiong, M Malmlöf… - Particle and fibre …, 2018 - Springer
Background Diesel exhaust particles (DEP) are a major component of outdoor air pollution.
DEP mediated pulmonary effects are plausibly linked to inflammatory and oxidative stress …

[PDF][PDF] The role of reactive oxygen species and oxidative stress in mediating particulate matter injury

T Xia, M Kovochich, A Nel - Clin Occup Environ Med, 2006 - academia.edu
Several plausible mechanisms have been proposed to explain the adverse health effects of
particulate matter (PM) in polluted ambient air [1]. To date, experimental support has been …

Cytokine responses induced by diesel exhaust particles are suppressed by PAR-2 silencing and antioxidant treatment, and driven by polar and non-polar soluble …

N Bach, AK Bølling, BC Brinchmann, AI Totlandsdal… - Toxicology letters, 2015 - Elsevier
Adsorbed soluble organics seem to be the main drivers of inflammatory responses induced
by diesel exhaust particles (DEP). The specific compounds contributing to this process and …