Frontotemporal dementia: implications for understanding Alzheimer disease

M Goedert, B Ghetti… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Frontotemporal dementia (FTD) comprises a group of behavioral, language, and movement
disorders. On the basis of the nature of the characteristic protein inclusions, frontotemporal …

Frontotemporal lobar degeneration: Pathogenesis, pathology and pathways to phenotype

DMA Mann, JS Snowden - Brain Pathology, 2017 - Wiley Online Library
Abstract Frontotemporal Lobar Degeneration (FTLD) is a clinically, pathologically and
genetically heterogeneous group of disorders that affect principally the frontal and temporal …

Frontotemporal dementia

DC Perry, BL Miller - Seminars in Neurology, 2013 - thieme-connect.com
Frontotemporal dementia (FTD) encompasses several clinical syndromes that involve a
progressive change in behavior and/or language; it is more common than Alzheimer's …

The molecular basis of frontotemporal dementia

M Neumann, M Tolnay, IRA Mackenzie - Expert reviews in molecular …, 2009 - cambridge.org
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. Familial FTD has been linked to mutations in several genes, including those encoding …

Phenotypic heterogeneity of monogenic frontotemporal dementia

A Benussi, A Padovani, B Borroni - Frontiers in aging neuroscience, 2015 - frontiersin.org
Frontotemporal dementia (FTD) is a genetically and pathologically heterogeneous disorder
characterized by personality changes, language impairment, and deficits of executive …

Changing perspectives on frontotemporal dementia: A review

JS Snowden - Journal of Neuropsychology, 2023 - Wiley Online Library
This article examines the evolution in understanding of frontotemporal dementia (FTD)
during the last four decades. A central theme is the recognition of heterogeneity. Originally …

Clinic, neuropathology and molecular genetics of frontotemporal dementia: a mini-review

X Pan, X Chen - Translational neurodegeneration, 2013 - Springer
Frontotemporal lobar degeneration (FTLD) represents a group of clinically,
neuropathologically and genetically heterogeneous disorders with plenty of overlaps …

The clinical spectrum of sporadic and familial forms of frontotemporal dementia

IOC Woollacott, JD Rohrer - Journal of neurochemistry, 2016 - Wiley Online Library
The term frontotemporal dementia (FTD) describes a clinically, genetically and
pathologically diverse group of neurodegenerative disorders. Symptoms of FTD can present …

Frontotemporal lobar degeneration: current concepts in the light of recent advances

S Kumar‐Singh, C Van Broeckhoven - Brain pathology, 2007 - Wiley Online Library
Work done over the past decade has led to a molecular understanding of frontotemporal
lobar degeneration (FTLD), a deadly disease that afflicts patients in mid‐life. It is a common …

Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies

IRA Mackenzie, M Neumann - Journal of neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The past decade has seen the discovery of several new FTD‐causing genetic …