Relationship of serum imatinib trough level and response in CML patients: long term follow-up
A Awidi, AO Ayed, N Bsoul, A Magablah, R Mefleh… - Leukemia research, 2010 - Elsevier
One hundred and three patients with Philadelphia chromosome or BCR-ABL positive
chronic myeloid leukemia (CML) in chronic phase who were on oral imatinib were included …
chronic myeloid leukemia (CML) in chronic phase who were on oral imatinib were included …
Correlation of plasma trough levels of imatinib with molecular response in patients with chronic myeloid leukemia
H Malhotra, P Sharma, S Bhargava… - Leukemia & …, 2014 - Taylor & Francis
The present study looked at the correlation between mean trough Imatinib plasma levels
and molecular response in 131 CML patients on imatinib. Patients receiving Glivec versus …
and molecular response in 131 CML patients on imatinib. Patients receiving Glivec versus …
Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia
S Picard, K Titier, G Etienne, E Teilhet, D Ducint… - Blood, 2007 - ashpublications.org
Using high-performance liquid chromatography–tandem mass spectrometry, we assessed
trough imatinib plasma levels in 68 patients with chronic myeloid leukemia (CML) who …
trough imatinib plasma levels in 68 patients with chronic myeloid leukemia (CML) who …
Trough plasma imatinib levels are correlated with optimal cytogenetic responses at 6 months after treatment with standard dose of imatinib in newly diagnosed chronic …
SK Sohn, SJ Oh, BS Kim, HM Ryoo… - Leukemia & …, 2011 - Taylor & Francis
To investigate the correlation of trough imatinib mesylate (IM) levels with cytogenetic or
molecular responses, we measured trough IM levels in patients with chronic myeloid …
molecular responses, we measured trough IM levels in patients with chronic myeloid …
Imatinib trough plasma levels do not correlate with the response to therapy in patients with chronic myeloid leukemia in routine clinical setting
E Faber, D Friedecký, K Mičová, Š Rožmanová… - Annals of …, 2012 - Springer
Association of trough imatinib plasma levels (IPL) with cytogenetic or molecular response to
treatment in patients with chronic myeloid leukemia (CML) was repeatedly reported. We …
treatment in patients with chronic myeloid leukemia (CML) was repeatedly reported. We …
The clinical relevance of imatinib plasma trough concentrations in chronic myeloid leukemia. A Belgian study
F Van Obbergh, L Knoops, T Devos, Y Beguin… - Clinical …, 2017 - Elsevier
This retrospective multicenter study in patients with chronic myeloid leukemia in chronic
phase was undertaken to confirm the clinical relevance of imatinib plasma concentrations …
phase was undertaken to confirm the clinical relevance of imatinib plasma concentrations …
Imatinib trough levels: a potential biomarker to predict cytogenetic and molecular response in newly diagnosed patients with chronic myeloid leukemia
Therapeutic drug monitoring of imatinib in patients with chronic myeloid leukemia (CML) is
an ongoing debate. We studied the influence of imatinib trough levels on therapeutic …
an ongoing debate. We studied the influence of imatinib trough levels on therapeutic …
[HTML][HTML] Association of the trough, peak/trough ratio of imatinib, pyridine–N-oxide imatinib and ABCG2 SNPs 34 G> A and SLCO1B3 334 T> G with imatinib response …
MM Omran, R Abdelfattah, HS Moussa… - Frontiers in …, 2020 - frontiersin.org
Imatinib mesylate (IM) is highly efficacious in the treatment of chronic myeloid leukemia
(CML). Therapeutic drug monitoring and pharmacogenetic screening are affirmed for better …
(CML). Therapeutic drug monitoring and pharmacogenetic screening are affirmed for better …
Adherence to the standard dose of imatinib, rather than dose adjustment based on its plasma concentration, is critical to achieve a deep molecular response in …
C Yoshida, T Komeno, M Hori, T Kimura, M Fujii… - International journal of …, 2011 - Springer
The correlation between imatinib (IM) trough plasma concentration (Cmin) and clinical
response was assessed in patients with chronic-phase chronic myeloid leukemia. The Cmin …
response was assessed in patients with chronic-phase chronic myeloid leukemia. The Cmin …
Drug monitoring of imatinib levels in patients undergoing therapy for chronic myeloid leukaemia: comparing plasma levels of responders and non-responders
N Singh, L Kumar, R Meena, T Velpandian - European journal of clinical …, 2009 - Springer
Purpose Imatinib mesylate is used as first line therapy in the treatment of chronic myeloid
leukaemia. This study was designed to study the correlation of plasma levels of imatinib with …
leukaemia. This study was designed to study the correlation of plasma levels of imatinib with …