[HTML][HTML] Effect of indacaterol on exercise endurance and lung hyperinflation in COPD

DE O'Donnell, R Casaburi, W Vincken… - Respiratory …, 2011 - Elsevier
Background Indacaterol is a novel, inhaled, once-daily ultra long-acting β 2-agonist (ultra-
LABA) for the treatment of COPD. This study investigated the effect of indacaterol on …

Indacaterol, a once‐daily beta2‐agonist, versus twice‐daily beta2‐agonists or placebo for chronic obstructive pulmonary disease

JB Geake, EJ Dabscheck… - Cochrane Database …, 2015 - cochranelibrary.com
Background Indacaterol is an inhaled long‐acting beta 2‐agonist that is administered once
daily and has been investigated as a treatment for chronic obstructive pulmonary disease …

Integrating indacaterol dose selection in a clinical study in COPD using an adaptive seamless design

PJ Barnes, SJ Pocock, H Magnussen, A Iqbal… - Pulmonary …, 2010 - Elsevier
BACKGROUND: The drug development process can be streamlined by combining the
traditionally separate stages of dose-finding (Phase IIb) and confirmation of efficacy and …

Bronchodilator effects of indacaterol and formoterol in patients with COPD

J Beier, KM Beeh, L Brookman, G Peachey… - Pulmonary …, 2009 - Elsevier
BACKGROUND: Resting inspiratory capacity (IC) reflects static hyperinflation in chronic
obstructive pulmonary disease (COPD). This study compared the effects of formoterol and …

Indacaterol improves lung hyperinflation and physical activity in patients with moderate chronic obstructive pulmonary disease-a randomized, multicenter, double …

H Watz, F Krippner, A Kirsten, H Magnussen… - BMC pulmonary …, 2014 - Springer
Background Indacaterol is a long-acting beta-2 agonist for once-daily treatment of COPD.
We evaluated the effects of indacaterol 150 μg on lung hyperinflation compared with …

Blinded 12-week comparison of once-daily indacaterol and tiotropium in COPD

R Buhl, LJ Dunn, C Disdier, C Lassen… - European …, 2011 - Eur Respiratory Soc
Two, once daily (qd) inhaled bronchodilators are available for the treatment of chronic
obstructive pulmonary disease (COPD): the β2-agonist indacaterol and the anticholinergic …

[HTML][HTML] Cost-utility analysis of indacaterol in Germany: a once-daily maintenance bronchodilator for patients with COPD

D Price, A Gray, R Gale, Y Asukai, L Mungapen… - Respiratory …, 2011 - Elsevier
INTRODUCTION: Indacaterol is a novel inhaled once-daily long-acting beta2-agonist
(LABA) for the maintenance treatment of COPD that has been compared to existing inhaled …

Bronchodilator efficacy of indacaterol, a novel once-daily β2-agonist, in patients with persistent asthma

DS Pearlman, L Greos, C LaForce, CJ Orevillo… - Annals of Allergy …, 2008 - Elsevier
BACKGROUND: Indacaterol is a novel once-daily inhaled β2-agonist in development for the
treatment of patients with asthma or chronic obstructive pulmonary disease. OBJECTIVE: To …

Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches

D Renard, M Looby, B Kramer, D Lawrence… - Respiratory …, 2011 - Springer
Background Indacaterol is a once-daily long-acting inhaled β 2-agonist indicated for
maintenance treatment of moderate-to-severe chronic obstructive pulmonary disease …

Indacaterol provides sustained 24 h bronchodilation on once‐daily dosing in asthma: a 7‐day dose‐ranging study

C LaForce, M Alexander, R Deckelmann, LM Fabbri… - Allergy, 2008 - Wiley Online Library
Background: Indacaterol is a novel, once‐daily β2‐agonist in development for the treatment
of asthma and chronic obstructive pulmonary disease. Studies were required to determine …