Synthesis, Crystal Structure, and Antifungal Activity of Quinazolinone Derivatives

R Zeng, C Huang, J Wang, Y Zhong, Q Fang, S Xiao… - Crystals, 2023 - mdpi.com
In this paper, four new compounds with quinazolinone structure were designed and
synthesized based on the special biological activity of quinazolinone. The four new …

Design, synthesis, and structure–activity relationship of quinazolinone derivatives as potential fungicides

JW Peng, XD Yin, H Li, KY Ma, ZJ Zhang… - Journal of Agricultural …, 2021 - ACS Publications
Plant diseases caused by phytopathogenic fungi reduce the yield and quality of crops. To
develop novel antifungal agents, we designed and synthesized eight series of …

Design, synthesis, and bioactivity of novel quinazolinone scaffolds containing pyrazole carbamide derivatives as antifungal agents

Z Lei, J Yao, H Liu, X Bai, X Gao, Q Pan… - Current Issues in …, 2022 - mdpi.com
In this study, 32 novel quinazolinone-scaffold-containing pyrazole carbamide derivatives
were designed and synthesized in a search for a novel fungicide against Rhizoctonia solani …

One-pot synthesis and antifungal activity against plant pathogens of quinazolinone derivatives containing an amide moiety

J Zhang, J Liu, Y Ma, D Ren, P Cheng, J Zhao… - Bioorganic & Medicinal …, 2016 - Elsevier
An efficient one-pot, three-component synthesis of quinazolinone derivatives containing 3-
acrylamino motif was carried out using CeO 2 nanoparticles as catalyst. Thirty-nine …

Synthesis, crystal structure, and antimicrobial evaluation of novel 4-oxyquinazoline derivatives containing a benzimidazole moiety

Y Yan, S Liu, L An, Y Yang, G Tian, X Bao - Journal of Molecular Structure, 2024 - Elsevier
To find more effective agricultural antimicrobial agents, a family of new 4-oxyquinazoline
derivatives bearing a benzimidazole moiety were synthesized and evaluated for their …

Design, synthesis and antifungal activity of novel 1, 4-pentadiene-3-one containing quinazolinone

R Zhou, W Zhan, C Yuan, T Zhang, P Mao… - International Journal of …, 2023 - mdpi.com
Twenty 1, 4-pentadiene-3-one derivatives containing quinazolinone (W1–W20) were
designed and synthesized. The bioactivity test results showed that some compounds had …

The synthesis of 6-(tert-butyl)-8-fluoro-2,3-dimethylquinoline carbonate derivatives and their antifungal activity against Pyricularia oryzae

L Cheng, R Zhang, H Wu, X Liu, T Xu - Frontiers of Chemical Science and …, 2019 - Springer
A series of novel 6-(tert-butyl)-8-fluoro-2, 3-dimethylquinoline carbonate derivatives were
designed and synthesized. Bioassay results showed that some of them exhibited good …

Design, synthesis, and antifungal evaluation of novel quinoline derivatives inspired from natural quinine alkaloids

GZ Yang, JK Zhu, XD Yin, YF Yan… - Journal of agricultural …, 2019 - ACS Publications
Inspired by quinine and its analogues, we designed, synthesized, and evaluated two series
of quinoline small molecular compounds (a and 2a) and six series of quinoline derivatives …

Novel 4(3H)‐Quinazolinone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Bioactivity Evaluation

W Xiang, T Cheng‐hao, W Guo‐lan… - Journal of Heterocyclic …, 2017 - Wiley Online Library
The aim of the present study is to design and synthesize a series of novel 4 (3H)‐
quinazolinone derivatives containing an isoxazole moiety and evaluate their antifungal …

Design and discovery of novel antifungal quinoline derivatives with acylhydrazide as a promising pharmacophore

YD Yang, YH He, KY Ma, H Li, ZJ Zhang… - Journal of Agricultural …, 2021 - ACS Publications
Inspired by natural 2-quinolinecarboxylic acid derivatives, a series of quinoline compounds
containing acylhydrazine, acylhydrazone, sulfonylhydrazine, oxadiazole, thiadiazole, or …