Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial
SE Nissen, EM Tuzcu, P Schoenhagen, BG Brown… - Jama, 2004 - jamanetwork.com
ContextStatin drugs reduce both atherogenic lipoproteins and cardiovascular morbidity and
mortality. However, the optimal strategy and target level for lipid reduction remain uncertain …
mortality. However, the optimal strategy and target level for lipid reduction remain uncertain …
Effect of two intensive statin regimens on progression of coronary disease
Background Statins reduce adverse cardiovascular outcomes and slow the progression of
coronary atherosclerosis in proportion to their ability to reduce low-density lipoprotein (LDL) …
coronary atherosclerosis in proportion to their ability to reduce low-density lipoprotein (LDL) …
Effect of intensive lipid lowering on progression of coronary atherosclerosis: evidence for an early benefit from the Reversal of Atherosclerosis with Aggressive Lipid …
SE Nissen - The American journal of cardiology, 2005 - Elsevier
Statins reduce both atherogenic lipoproteins and high-sensitivity C-reactive protein
(hsCRP). The optimal strategy for administration of lipid-lowering agents has evolved …
(hsCRP). The optimal strategy for administration of lipid-lowering agents has evolved …
Statins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosis
SJ Nicholls, EM Tuzcu, I Sipahi, AW Grasso… - Jama, 2007 - jamanetwork.com
ContextStatins reduce low-density lipoprotein cholesterol (LDL-C) levels and slow
progression of coronary atherosclerosis. However, no data exist describing the relationship …
progression of coronary atherosclerosis. However, no data exist describing the relationship …
Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial
ContextPrior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of
atherosclerosis progression with statin therapy but have not shown convincing evidence of …
atherosclerosis progression with statin therapy but have not shown convincing evidence of …
Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease
Background Percutaneous coronary revascularization is widely used in improving symptoms
and exercise performance in patients with ischemic heart disease and stable angina …
and exercise performance in patients with ischemic heart disease and stable angina …
[HTML][HTML] Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease
SE Nissen, EM Tuzcu, P Schoenhagen… - … England Journal of …, 2005 - Mass Medical Soc
Background Recent trials have demonstrated better outcomes with intensive than with
moderate statin treatment. Intensive treatment produced greater reductions in both low …
moderate statin treatment. Intensive treatment produced greater reductions in both low …
High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial
TR Pedersen, O Faergeman, JJP Kastelein, AG Olsson… - Jama, 2005 - jamanetwork.com
ContextEvidence suggests that more intensive lowering of low-density lipoprotein
cholesterol (LDL-C) than is commonly applied clinically will provide further benefit in stable …
cholesterol (LDL-C) than is commonly applied clinically will provide further benefit in stable …
Coronary atheroma volume and cardiovascular events during maximally intensive statin therapy
Aims The impact of baseline coronary plaque burden on the clinical outcome in patients
receiving aggressive low-density lipoprotein cholesterol (LDL-C) lowering therapy to levels< …
receiving aggressive low-density lipoprotein cholesterol (LDL-C) lowering therapy to levels< …
Effect of intensive atorvastatin therapy on coronary atherosclerosis progression, composition, arterial remodeling, and microvascular function.
P Eshtehardi, MC McDaniel, SS Dhawan… - The Journal of …, 2012 - europepmc.org
Background There is a discrepancy between the marked reduction in adverse events with
statins and their modest effect on atheroma regression. We hypothesized that, in a Western …
statins and their modest effect on atheroma regression. We hypothesized that, in a Western …
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