The pros and cons of prophylactic central compartment lymph node dissection for papillary thyroid carcinoma

EL Mazzaferri, GM Doherty, DL Steward - Thyroid, 2009 - liebertpub.com
A well-established feature of papillary thyroid carcinoma (PTC) is it propensity to
metastasize to cervical lymph nodes in the central and lateral compartments. Currently, there …

Frozen biopsy of central compartment in papillary thyroid cancer: quantitative nodal analysis

YS Lim, SW Choi, YS Lee, JC Lee, BJ Lee… - Head & …, 2013 - Wiley Online Library
Background Nodal metastasis in papillary thyroid cancer (PTC) usually occurs in the central
compartment of the ipsilateral neck and spreads laterally. The purpose of this study was to …

Long-term outcomes of patients with papillary thyroid cancer who did not undergo prophylactic central neck dissection

H Huang, L Wu, W Liu, J Liu, Y Liu… - Journal of Cancer …, 2020 - journals.lww.com
Aims: The role of prophylactic central neck dissection (CND) in the management of papillary
thyroid carcinoma (PTC) is controversial. This study reports outcomes of an observational …

Occult contralateral lateral lymph node metastases in unilateral N1b papillary thyroid carcinoma

H Bohec, I Breuskin, J Hadoux, M Schlumberger… - World Journal of …, 2019 - Springer
Objective Therapeutic lateral neck dissection (ND) is recommended for N1b papillary thyroid
carcinoma (PTC), while prophylactic contralateral lateral ND is not. Given the paucity of data …

The extent of lymph node yield in central neck dissection can be affected by preoperative and intraoperative assessment and alter the prognosis of papillary thyroid …

JQ Hu, D Wen, B Ma, TT Zhang, T Liao, X Shi… - Cancer …, 2020 - Wiley Online Library
Background Lymph node yield (LNY) was implemented in the stratification of papillary
thyroid cancer (PTC) patients. The effect of LNY may be related to the extent of surgery. This …

A meta-analysis of the effect of prophylactic central compartment neck dissection on locoregional recurrence rates in patients with papillary thyroid cancer

TS Wang, K Cheung, F Farrokhyar, SA Roman… - Annals of surgical …, 2013 - Springer
Background It is not known whether prophylactic central compartment neck dissection
(pCCND) in conjunction with total thyroidectomy decreases rates of locoregional recurrence …

Lymph node recurrence in patients with N1b papillary thyroid carcinoma who underwent unilateral therapeutic modified radical neck dissection

Y Ito, T Kudo, Y Takamura, K Kobayashi, A Miya… - World journal of …, 2012 - Springer
Background Therapeutic modified radical neck dissection (MND) is a mandatory surgical
procedure for patients with papillary thyroid carcinoma (PTC) having clinical lateral node …

Clinical significance of prophylactic central compartment neck dissection in the treatment of clinically node-negative papillary thyroid cancer patients

C Gambardella, E Tartaglia, A Nunziata, G Izzo… - World journal of surgical …, 2016 - Springer
Background Lymph nodal involvement is very common in differentiated thyroid cancer, and
in addition, cervical lymph node micrometastases are observed in up to 80% of papillary …

Identifying risk factors of recurrence for clinically node negative papillary thyroid carcinoma with pathologic N1a

YJ Ryu, JS Cho, MH Park, JH Yoon - BMC surgery, 2019 - Springer
Background Whether or not to perform prophylactic central lymph node dissection (CLND) in
the case of clinically node-negative papillary thyroid cancer (PTC) is controversial. The …

Prophylactic central neck dissection has no advantage in patients with metastatic papillary thyroid cancer to the lateral neck

NN Carmel‐Neiderman, A Mizrachi… - Journal of Surgical …, 2021 - Wiley Online Library
Background Papillary thyroid cancer (PTC) usually metastasizes via lymphatic channels in a
sequential fashion, first to the central compartment, followed by the lateral neck. PTC …