Emerging therapies in Parkinson diseaserepurposed drugs and new approaches

A Elkouzi, V Vedam-Mai, RS Eisinger… - Nature Reviews …, 2019 - nature.com
… compounds, repurposed drugs and new technologies. In this Review, we focus on disease-…
We review cellular therapies and repurposed drugs, such as nilotinib, inosine, isradipine, …

Repurposing drugs to treat l-DOPA-induced dyskinesia in Parkinson's disease

TH Johnston, AMB Lacoste, NP Visanji, AE Lang… - …, 2019 - Elsevier
… discuss the opportunity for repurposing drugs for use in l-DOPA-induced dyskinesia (LID)
in Parkinson's disease. LID is a particularly suitable indication for drug repurposing given its …

Drug repurposing in Parkinson's disease

D Athauda, T Foltynie - CNS drugs, 2018 - Springer
repurposed drugs that are currently being evaluated in clinical trials for their potential disease
Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a …

Drug repurposing strategies of relevance for Parkinson's disease

EJR Fletcher, T Kaminski, G Williams… - Pharmacology …, 2021 - Wiley Online Library
drugs so the disease progresses unchecked. Standard drug discovery programs for disease
provided key insights into the pathogenesis of Parkinson's disease but, of the many positive …

[HTML][HTML] Teaching the basics of repurposing mitochondria-targeted drugs: from Parkinson's disease to cancer and back to Parkinson's disease

B Kalyanaraman - Redox Biology, 2020 - Elsevier
… Introduction: Parkinson's disease and … of repurposing mitochondria-targeted drugs that are
modifications of natural compounds and FDA-approved drugs for treating Parkinson's disease

Recent advances in drug repurposing for Parkinson's disease

X Chen, G Gumina, KG Virga - Current Medicinal Chemistry, 2019 - ingentaconnect.com
drug repurposing. With the successful clinical introduction of several repurposed drugs for
Parkinson’s disease, drug repurposing … development of novel drugs for this disease. In this …

Parkinson's disease drug development since 1999: A story of repurposing and relative success

DM Boucherie, GS Duarte, T Machado… - … Parkinson's disease, 2021 - content.iospress.com
… We examined the ICTRP to determine the characteristics of Parkinson’s disease trials … the
history of drug development in Parkinson’s disease, characterize trends in drug development, …

Repurposing anti-diabetic drugs for the treatment of Parkinson's disease: rationale and clinical experience

T Foltynie, D Athauda - Progress in Brain Research, 2020 - Elsevier
… The most pressing need in Parkinson's disease (PD) clinical practice is … Parkinson's disease
and therefore avoid the onset of the most disabling, dopa-refractory symptoms of the disease

Drug reprofiling history and potential therapies against Parkinson's disease

K Latif, A Ullah, AD Shkodina, DI Boiko… - Frontiers in …, 2022 - frontiersin.org
… We describe strategies of drug repurposing for Parkinson’s disease, which is a
neurodegenerative … properties of drugs used in the treatment of Parkinson's disease. properties of …

Drug repurposing against Parkinson's disease by text mining the scientific literature

Y Zhu, W Jung, F Wang, C Che - Library Hi Tech, 2020 - emerald.com
… We aimed to develop a drug repurposing pipeline comprising … section, drug repurposing
against Parkinson's disease is not … drug repurposing approach against Parkinson's disease is …