CD8 T cell responses to infectious pathogens

P Wong, EG Pamer - Annual review of immunology, 2003 - annualreviews.org
CD8 T cell responses. Thus, for many ofthe pathogens discussed in this review, CD8 T cell
responses can … The CD8 T cell response isfocused on an H-2K b -restricted immunodominant …

[HTML][HTML] Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis

T Prezzemolo, G Guggino, MP La Manna… - Frontiers in …, 2014 - frontiersin.org
… These functions are also used by MHC-class Ib-restricted CD8 + T cells, suggesting a
role … In conclusion, Mtb-specific CD8 T cell response, as defined by the qualitative and the …

Functional characterization of MHC class II-restricted CD8+ CD4− and CD8− CD4− T cell responses to infection in CD4−/− mice

EL Pearce, DJ Shedlock, H Shen - The Journal of Immunology, 2004 - journals.aai.org
… We show that CD4 −/− mice mounted a strong CD8 + T cell response to MHCII-restricted
MHCII-restricted, epitope-specific CD8 + T cells are readily detectable at the single-cell level…

Monitoring CD8 T cell responses to NY-ESO-1: correlation of humoral and cellular immune responses

E Jäger, Y Nagata, S Gnjatic, H Wada… - Proceedings of the …, 2000 - National Acad Sciences
CD8 + T cell responses to HLA-A2-restricted NY-ESO-1 peptides were detected in 10 of 11
patients with NY-ESO-1 antibody, but not in patients lacking antibody or in patients with NY-…

Regulatory CD4+CD25+ T Cells Restrict Memory CD8+ T Cell Responses

M Kursar, K Bonhagen, J Fensterle, A Köhler… - The Journal of …, 2002 - rupress.org
… Our results demonstrate that CD4 + T cells control the CD8 + T cell response in two … of a
CD8 + T cell responses and later they restrain the strength of the CD8 + T cell memory response. …

An MHC class Ib–restricted CD8 T cell response confers antiviral immunity

PA Swanson, CD Pack, A Hadley, CR Wang… - The Journal of …, 2008 - rupress.org
… Q9-restricted VP2 epitope–specific CD8 T cells to PyV … class Ib–restricted antiviral CD8
T cell response that contributes … MHC class Ib–restricted CD8 T cell responses in other viral …

[HTML][HTML] Specificity, restriction and effector mechanisms of immunoregulatory CD8 T cells

M Vukmanovic-Stejic, MJ Thomas, A Noble… - …, 2001 - ncbi.nlm.nih.gov
… A number of studies provide strong evidence for a direct role of CD8 T cells in
downregulation of CD4 T-cell responses to autoantigens and foreign antigens. In mice and rats …

Pathogen-specific CD8 T cell responses are directly inhibited by IL-10

PS Biswas, V Pedicord, A Ploss, E Menet… - The Journal of …, 2007 - journals.aai.org
cell activation/proliferation remains unknown. Herein, we demonstrate that primary and memory
CD8 T cell responses … be exploited to either restrict CD8 T cell responses in the setting of …

[HTML][HTML] Dissecting the multifactorial causes of immunodominance in class I–restricted T cell responses to viruses

W Chen, LC Antón, JR Bennink, JW Yewdell - Immunity, 2000 - cell.com
… sensitive T CD8 + response. Inefficient antigen processing by virus-infected cells accounts
… determinants reflects limitations in T cell responses unrelated to TCR diversity or sensitivity. …

Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection

DJD Sourdive, K Murali-Krishna, JD Altman… - The Journal of …, 1998 - rupress.org
… L d -restricted NP118–126 stimulus, the Vβ10 + CD8 + population is ignorant of the K d -…
CD8 + T cell response to LCMV, we applied this approach to characterize virus-specific T cells