Cell surface protein glycosylation in cancer

MN Christiansen, J Chik, L Lee, M Anugraham… - …, 2014 - Wiley Online Library
… altered glycosylation patterns on the surface of cancer cells disrupt normal cellular functions
… trends of altered glycosylation to those found on the cancer cell surface, which include a …

[HTML][HTML] Roles of glycosylation at the cancer cell surface: opportunities for large scale glycoproteomics

T Čaval, F Alisson-Silva, F Schwarz - Theranostics, 2023 - ncbi.nlm.nih.gov
… for an unbiased interrogation of cell surface glycosylation status. Here … glycosylation at the
surface of cancer cell and describe selected examples of receptors with aberrant glycosylation

Glycosylation in cancer: Selected roles in tumour progression, immune modulation and metastasis

JG Rodrigues, M Balmaña, JA Macedo, J Poças… - Cellular …, 2018 - Elsevier
… and on the regulation of tumour cell-cell adhesion and cell-matrix … cancer cells and the
tumour microenvironment. In this review, we summarize the roles of glycan alterations in tumour

Role of protein glycosylation in cancer metastasis

L Oliveira-Ferrer, K Legler, K Milde-Langosch - Seminars in cancer biology, 2017 - Elsevier
… Although altered glycosylation has been detected in human cancer cells decades ago, …
glycosylation and its role in tumour progression. Many proteins, which are heavily glycosylated, ie …

Glycosylation in cancer: mechanisms and clinical implications

SS Pinho, CA Reis - Nature Reviews Cancer, 2015 - nature.com
… This Review discusses the roleglycosylation of key growth factors receptors, which modulates
their activity and signalling 161 . Expression of gangliosides in the cancer cell membrane

[HTML][HTML] Altered cell adhesion and glycosylation promote cancer immune suppression and metastasis

H Läubli, L Borsig - Frontiers in immunology, 2019 - frontiersin.org
… This mini review addresses the role of cell adhesion and … of altered glycosylation as a
ubiquitous characteristic of cancercancer cells through the activation of Wnt signaling (29). Tumor …

Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer

J Zhang, P Ten Dijke, M Wuhrer, T Zhang - Protein & cell, 2021 - academic.oup.com
… in the metastatic process by which cancer cells gain the ability to … effects on cells are mediated
by its receptors on the cell surface. … that are involved in cancer progression. Thereafter, we …

Cell migration—the role of integrin glycosylation

ME Janik, A Lityńska, P Vereecken - Biochimica et Biophysica Acta (BBA) …, 2010 - Elsevier
cell surface receptors are glycosylated, so that heterogeneous glycan moieties decorate the
extracellular regions of membrane… and malignant ureter cancer cells interact with collagen IV…

[HTML][HTML] Altered tumor-cell glycosylation promotes metastasis

I Häuselmann, L Borsig - Frontiers in oncology, 2014 - frontiersin.org
… -cell-surface glycans in tumor-cell migration, adhesion, and metastasis. This review addresses
the role of cancer-… aggregation of cancer cells, which protects cancer cells from apoptosis …

[HTML][HTML] Hallmarks of glycosylation in cancer

J Munkley, DJ Elliott - Oncotarget, 2016 - ncbi.nlm.nih.gov
… Glycans have roles in cancer cell signalling, tumour cell dissociation … glycosylation patterns
of cell surface and secreted glycoproteins occur during malignant transformation and cancer