Conservation and divergence in eukaryotic DNA methylation

T Lee, J Zhai, BC Meyers - Proceedings of the National …, 2010 - National Acad Sciences
methylation sequence contexts, cytosine methylation is … adaptations and conservation of
DNA methylation, inevitably … For instance, the function of conserved, genic methylation is still …

Conservation and divergence of methylation patterning in plants and animals

S Feng, SJ Cokus, X Zhang, PY Chen… - Proceedings of the …, 2010 - National Acad Sciences
… , determining precise genome-scale methylation patterns has been a … sequencing technology.
In this paper, we generated shotgun bisulfite sequencing data to profile DNA methylation

Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes

Z Su, L Han, Z Zhao - Epigenetics, 2011 - Taylor & Francis
… New approaches combining BS conversion and next-generation sequencing allow us to
measure the DNA methylation level more accurately and comprehensively. In addition to …

Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation

J Zhou, RL Sears, X Xing, B Zhang, D Li… - BMC genomics, 2017 - Springer
… Conserved DNA methylation is associated with conservation of … conservation of primary
genomic sequences. We found that the evolutionary dynamics of tissue-specific DNA methylation

Conservation of DNA methylation in dipteran insects

J Marhold, N Rothe, A Pauli, C Mund… - Insect Molecular …, 2004 - Wiley Online Library
… However, the high conservation of the protein sequences has … high conservation of Dnmt2
open reading frames in all species tested. In addition, significant amounts of DNA methylation

Determining the conservation of DNA methylation in Arabidopsis

N Widman, SE Jacobsen, M Pellegrini - Epigenetics, 2009 - Taylor & Francis
… To estimate the conservation of methylation in these aligned sequences the Pearson
correlations between the paired values of each gene or repeat was then computed. …

A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates

H Al Adhami, AF Bardet, M Dumas, E Cleroux… - BMC biology, 2022 - Springer
… We analyze the evolutionary conservation of DNA methylation … of DNA methylation in
vertebrate cells by DNA methylation … CG-rich sequences are more frequently methylated in germ …

DNA methylation is associated with an increased level of conservation at nondegenerate nucleotides in mammals

TJ Chuang, FC Chen - Molecular biology and evolution, 2014 - academic.oup.com
DNA methylation and the conservation of individual nucleotides are dependent on the type of
exonic sequence (… ’s comments in that DNA methylation in different sequence contexts may …

Functional conservation of DNA methylation in the pea aphid and the honeybee

BG Hunt, JA Brisson, SV Yi… - Genome biology and …, 2010 - academic.oup.com
… Surprisingly, in contrast to our results from analysis of DNA sequence identity, we found
that densely methylated genes with detectable orthologs may be under less constraint at the …

Beyond restriction modification: epigenomic roles of DNA methylation in prokaryotes

BP Anton, RJ Roberts - Annual Review of Microbiology, 2021 - annualreviews.org
… , DNA methylation is an epigenetic signal capable of altering the interpretation of genetic
information without change to the DNA sequence itself. … far less sequence conservation than the …