Study of the interaction of an anticancer drug with human and bovine serum albumin: spectroscopic approach

PB Kandagal, S Ashoka, J Seetharamappa… - … of pharmaceutical and …, 2006 - Elsevier
The interactions between gemcitabine hydrochloride (GEM) and bovine serum albumin (BSA)
or human serum albumin (HSA) have been studied by spectroscopic techniques. By the …

Investigating the interaction of anticancer drug temsirolimus with human transferrin: Molecular docking and spectroscopic approach

A Shamsi, A Ahmed, MS Khan… - Journal of Molecular …, 2018 - Wiley Online Library
drug temsirolimus and human transferrin (hTF) was investigated employing spectroscopic
and molecular docking approach. … in hTF in UV spectroscopy suggestive of complex formation …

Electrochemical studies and spectroscopic investigations on the interaction of an anticancer drug with DNA and their analytical applications

SS Kalanur, U Katrahalli, J Seetharamappa - Journal of Electroanalytical …, 2009 - Elsevier
… and binding ratio between DNA and drug are calculated to be 2.22 × 10 6 M −1 and 1:2,
respectively. Based on electrochemical and spectroscopic results, we concluded that the mode …

[HTML][HTML] NMR spectroscopy as a tool to investigate the structural basis of anticancer drugs

WH Gmeiner - Current medicinal chemistry, 1998 - books.google.com
… to consideration of NMR spectroscopic investigations that involve anticancer agents that
target … of studies that can presently be conducted using NMR spectroscopy will first be given. …

In vitro anticancer drug sensitivity sensing through single-cell Raman spectroscopy

J Wang, K Lin, H Hu, X Qie, WE Huang, Z Cui, Y Gong… - Biosensors, 2021 - mdpi.com
… The eight anticancer drugs used in this study were non-targeted drugs (cisplatin, gemcitabine,
and monomethyl auristatin E (MMAE)) and targeted drugs (osimertinib, afatinib, crizotinib, …

FTIR spectral signature of anticancer drugs. Can drug mode of action be identified?

A Mignolet, A Derenne, M Smolina, BR Wood… - … et Biophysica Acta (BBA …, 2016 - Elsevier
… and anti-cancer drugs. Results accumulated so far tend to demonstrate that infrared
spectroscopy … of using IR spectroscopy to screen and classify drugs according to modes of action. …

Study of interactions of an anticancer drug neratinib with bovine serum albumin: spectroscopic and molecular docking approach

TA Wani, AH Bakheit, MA Abounassif… - Frontiers in chemistry, 2018 - frontiersin.org
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides
valuable information in the drug development. This study was designed to evaluate the binding …

[HTML][HTML] Spectroscopic studies of the effects of anticancer drug mitoxantrone interaction with calf-thymus DNA

S Agarwal, DK Jangir, R Mehrotra - Journal of Photochemistry and …, 2013 - Elsevier
… In this study, we investigated the interaction of anticancer drug mitoxantrone with calf thymus
DNA using spectroscopic techniques. Several spectral changes were observed after the …

First Evidence of the Liposome-Mediated Deintercalation of Anticancer Drug Doxorubicin from the Drug–DNA Complex: A Spectroscopic Approach

A Das, C Adhikari, D Nayak, A Chakraborty - Langmuir, 2016 - ACS Publications
Biocompatible liposomes were used for the first time to study the deintercalation process of
a prominent anticancer drug, doxorubicin (DOX), from doxorubicin-intercalated DNA (DOX–…

[HTML][HTML] IR spectroscopy as a new tool for evidencing antitumor drug signatures

R Gasper, J Dewelle, R Kiss, T Mijatovic… - … et Biophysica Acta (BBA …, 2009 - Elsevier
… of using infrared spectroscopy for diagnostic purposes at the … of cells exposed to anti-cancer
drugs could offer a unique … changes induced by potential anti-cancer drugs. Ouabain is one …