Rationale of mesenchymal stem cell therapy in kidney injury

V Cantaluppi, L Biancone, A Quercia… - … Journal of Kidney …, 2013 - Elsevier
… After kidney injury, it has been shown that bone marrow–derived stem cells and kidney
resident stem cells may participate in kidney repair. However, it is widely accepted that the …

Bioluminescence imaging to monitor the in vivo distribution of administered mesenchymal stem cells in acute kidney injury

F Tögel, Y Yang, P Zhang, Z Hu… - American Journal of …, 2008 - journals.physiology.org
… track and quantify administered cells in vivo. Acute kidney injury (AKI) is a serious and
common clinical problem with high morbidity and mortality (18). Cell therapy is a promising new …

Cell therapy using human induced pluripotent stem cell-derived renal progenitors ameliorates acute kidney injury in mice

T Toyohara, SI Mae, SI Sueta, T Inoue… - Stem cells …, 2015 - academic.oup.com
cells has therapeutic effectiveness in mouse models of acute kidney injury induced by
ischemia/reperfusion injury… from trophic effects by the renal progenitor cells, and it identifies the …

Protection of mesenchymal stem cells on acute kidney injury

JJ Zhao, JL Liu, L Liu, HY Jia - Molecular medicine …, 2014 - spandidos-publications.com
… determine the protection of allogeneic bone marrow mesenchymal stem cells (BMSCs) on
an ischaemia/reperfusion (I/R)‑induced acute kidney injury (AKI) rat model and to investigate …

[HTML][HTML] Mesenchymal stem cell therapy in acute kidney injury (AKI): review and perspectives

C Sávio-Silva, PE Soinski-Sousa… - Revista da Associação …, 2020 - SciELO Brasil
… best route of administration, the number of cells per administration and also the number of …
and chronic kidney injury, understanding the interaction between MSCs and other tissue cells, …

[HTML][HTML] In search of mechanisms associated with mesenchymal stem cell-based therapies for acute kidney injury

DC de Almeida, C Donizetti-Oliveira… - The Clinical …, 2013 - ncbi.nlm.nih.gov
… (AKI) is classically described as a rapid loss of kidney function. … Mesenchymal stem cell (MSC)
based therapies have … new alternative for treating kidney injuries. Numerous experimental …

[HTML][HTML] Protective actions of administered mesenchymal stem cells in acute kidney injury: relevance to clinical trials

C Westenfelder, FE Togel - Kidney international supplements, 2011 - Elsevier
… Current therapies for acute kidney injury remain primarily supportive and … kidney injury
were treated with bone marrow-derived, culture-expanded allogeneic mesenchymal stem cells. …

Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia–reperfusion-induced acute and chronic kidney injury

S Gatti, S Bruno, MC Deregibus, A Sordi… - Nephrology Dialysis …, 2011 - academic.oup.com
… Several studies demonstrated that mesenchymal stem cells (MSCs) reverse acute kidney
injury (AKI) by a paracrine mechanism rather than by MSC transdifferentiation. We recently …

Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury

HY Choi, SJ Moon, BB Ratliff, SH Ahn, A Jung, M Lee… - PloS one, 2014 - journals.plos.org
Cell therapy using pluripotent MSCs to treat kidney injury has … stem cells home to injured
tissue and exert their beneficial effects by differentiating into targets cells and replacing injured

Mesenchymal stem cells: a promising therapeutic tool for acute kidney injury

RE Selim, HH Ahmed, SH Abd-Allah, GM Sabry… - Applied biochemistry …, 2019 - Springer
… The outcomes of the present research offer convincing evidence that stem cell-based therapy
represents the potential therapeutic approach against acute kidney injury. The success of …