[HTML][HTML] Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors

YH Shen, J Godlewski, J Zhu, P Sathyanarayana… - Journal of Biological …, 2003 - ASBMB
… the stress-activated MLK-SEK-JNK-Jun pathway and the ERK/MAPK pathway, and suggest
that sustained activation of the JNK pathway can result in the attenuation of the mitogen-…

[HTML][HTML] Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells

A Mansouri, LD Ridgway, AL Korapati, Q Zhang… - Journal of Biological …, 2003 - ASBMB
activation of MAPK pathways correlated with CDDP-induced apoptosis. A strong sustained
activation of both pathways … apoptosis; this activation of both JNK and p38 MAPK in CDDP-…

Mitogen‐activated protein kinases and reactive oxygen species: how can ROS activate MAPK pathways?

Y Son, YK Cheong, NH Kim, HT Chung… - Journal of signal …, 2011 - Wiley Online Library
pathways by ROS. This paper will focus on the putative mechanisms by which ROS can
activate MAPK pathways … consequences of sustained activation of MAPK pathways may include …

Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases

TC Grammer, J Blenis - Oncogene, 1997 - nature.com
… the MAPK pathway and investigate the point of signal divergence between the pp70S6k and
MAPK pathways… To further examine the possible causes for the sustained MAPK activity, we …

[HTML][HTML] Sustained activation of the mitogen-activated protein kinase pathway: a mechanism underlying receptor tyrosine kinase specificity for matrix metalloproteinase …

LJ McCawley, S Li, EV Wattenberg… - Journal of Biological …, 1999 - ASBMB
… apparent paradox that although the MAPK pathway is essential for receptor … activation
of the ERK and JNK pathways was readily detected, sustained activation of p42/p44 ERK/MAPK

Spaced stimuli stabilize MAPK pathway activation and its effects on dendritic morphology

GY Wu, K Deisseroth, RW Tsien - Nature neuroscience, 2001 - nature.com
… Considering the possible importance of sustained phosphorylation of dendritic MAPK, we
closely examined the signaling events that led up to its initial establishment. Depolarization-…

Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species

WS Wu, JR Wu, CT Hu - Cancer and Metastasis Reviews, 2008 - Springer
activate ERK for cell proliferation, ligands that stimulate cell migration and invasion triggered
sustained activation … loop for sustained activation of the down stream MAPK signal (Fig. 3). …

[HTML][HTML] Understanding MAPK signaling pathways in apoptosis

J Yue, JM López - International journal of molecular sciences, 2020 - mdpi.com
sustained activation of the JNK/p38 signaling pathways (… are activated early by osmostress
and that sustained activation … Later, when caspase-3 is activated, JNK1-2 is proteolyzed at …

Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53

SW Lee, L Fang, M Igarashi, T Ouchi… - Proceedings of the …, 2000 - National Acad Sciences
… The mitogen-activated protein kinase (MAPK) … of MAPK activation can profoundly influence
the biological response observed. We demonstrated that a sustained activation of MAPK

[HTML][HTML] Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of …

FK Racke, K Lewandowska, S Goueli… - Journal of Biological …, 1997 - ASBMB
… effects via the ERK/MAP kinase pathway, expression in K562 … that sustained activation of
the ERK/MAP kinase pathway for … that the sustained activation of the ERK/MAP kinase pathway