… treated with systemic therapy based on molecular profiling. Further study of these mutations
may lead to the development of more targeted therapies for selected patient populations. …

… Additional systemic therapy is provided as well. Certain systemic therapies augment radiation
effect and so are started prior to EBRT Citation[25]. Traditionally, most ATC patients have a …

… Such patients most often require systemic therapy beyond radioactive iodine (RAI), with the
… other systemic therapies, prompting this study of the extent to which such cancers might …

… , which typically includes complete resection followed by high dose radiation and
systemic therapy, have shown the greatest improvement in OS [1,22,29,[31], [32], [33]]. …

… When considering all types of thyroid cancer, it most often occurs in the fifth decade of life.
Thyroid cancer … Systemic therapies are considered under these circumstances. However, …

… Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer…
Radiation, systemic therapy, or the combination given after surgery with curative intention is …

… For patients with RAI-refractory DTC, a disease for which there were previously few treatment
options available, the advent of targeted systemic therapies represents a major advance. …

… If the lesions are centimetric, even multiple, an active surveillance with 6 month controls
should be preferred to systemic therapy. Similarly, if the lesion is big but unique the possibility of …

… Anaplastic thyroid cancer (ATC), in contrast, is perhaps the … more effective systemic therapies
for advanced thyroid cancers (… rationale for the application of available systemic therapies. …

… A systematic search was conducted using Excerpta Medica Database … therapies and systemic
therapies (targeted chemotherapy, redifferentiation therapy, immunotherapy, gene therapy…