… To practice systems biology, one must capture and integrate global sets of biological
data from as many hierarchical levels of information as possible (see Figure 1). These could …

… Systems biology requires the development and application … tools to carry out systems approach
and, accordingly, requires a … systems biology will be a powerful engine driving biology in …

… The project of localising and defining biological systems can instead be developed within
existing practice. This project could accomplish two things: it could make the new …

… In this paper, we describe the current status of a fully integrated and fully operational
systems biology production platform. This platform has resulted from a 6-year effort which has …

… Best practices in manual reconstruction call for a module-by-module reconstruction where
each addition is tested for accuracy and effect on the functions of the network. In the rest of …

… Furthermore, best practices in documenting published research results should be followed.
For example, the Reproducibility Initiative advices researchers to first conduct a direct …

… In silico systems biology as intended in this book relies on the definition of systems
biology in terms of modeling and simulations of biological processes. Ultimately, the goal of …

… of systems principles to medicine reviewed in this article, the breadth of the success of this
approach has yet to be realized but will, no doubt, revolutionize the science and practice of …

… often talk about integrating disciplines, this usually boils down to the three sets of integrative
practices we outlined in Section 3. Multidisciplinary capacities certainly inform and even …

… methodologies: Systems Biology and Pharmacometrics. From the Systems Biology perspective
… As a consequence, the transition of Systems Biology to Systems Medicine in practice will, …