DNA methylation, genomic silencing, and links to nutrition and cancer

DC McCabe, MA Caudill - Nutrition reviews, 2005 - academic.oup.com
… Aberrant DNA methylation is linked to numerous pathologies, … DNA methylation and its
functions, to examine the relationship between dietary methyl insufficiency and DNA methylation, …

Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease

L Yu, LB Chibnik, GP Srivastava, N Pochet… - JAMA …, 2015 - jamanetwork.com
… with both amyloid and tangles. An attenuated association of DNA methylation would be
evidence of mediation. We found that DNA methylation associations with tau tangle density were …

DNA methylation changes in a gene-specific manner in different developmental stages of Drosophila melanogaster

CS Panikar, MS Paingankar, S Deshmukh… - Current Science, 2017 - JSTOR
… of a particular gene and its methylation status. In this … methylated in other life stages. Our
analysis while providing a me thylation map also suggests that gene-specific DNA methylation

A preliminary comparison of the methylome and transcriptome from the prefrontal cortex across Alzheimer's disease and Lewy body dementia

DW Fisher, J Tulloch, CE Yu… - Journal of Alzheimer's …, 2023 - content.iospress.com
… amyloid plaques and neurofibrillary tangles that meet … structure changes, DNA oxidation,
and DNA methylation are some of … most advanced iteration of DNA methylation microarrays, the …

Genome-Wide DNA Methylation Profiles of Neurodevelopmental Disorder Genes in Mouse Placenta and Fetal Brain Following Prenatal Exposure to Polychlorinated …

BI Laufer, KE Neier, AE Valenzuela, DH Yasui… - bioRxiv, 2021 - biorxiv.org
… PCB exposure on placental and fetal brain DNA methylation profiles from the same mice in
a … placental DNA methylation patterns could serve as predictors of brain DNA methylation. …

[HTML][HTML] Integrated Genome-Wide Analysis of DNA Methylation and Gene Expression in the Hippocampi of 5xFAD Alzheimer's Disease Mouse Model

S Lee, HJ Lee, JM Chun, B Jung, J Kim… - Journal of Integrative …, 2024 - imrpress.com
… : DNA methylation forms 5-methylcytosine and its regulation in the hippocampus is critical for
learning and memory. Indeed, dysregulation of DNA methylation is … -wide DNA methylation

Psychosis-associated DNA methylomic variation in Alzheimer's disease cortex

E Pishva, B Creese, AR Smith, W Viechtbauer… - Neurobiology of …, 2020 - Elsevier
… There was no significant difference in the distribution of neurofibrillary tangle Braak stage …
The aim of this study was to identify distinct patterns of DNA methylation associated with the …

Discovery of DNA methylation markers in cervical cancer using relaxation ranking

M Ongenaert, GBA Wisman, HH Volders… - BMC medical …, 2008 - Springer
… Verification of the DNA methylation state of the 10 highest-ranking genes … DNA methylation
in cervical carcinomas. Of these 7 genes, 3 (SST, HTRA3 and NPTX1) are not methylated in …

Identification of subtypes of Barrett's esophagus and esophageal adenocarcinoma based on DNA methylation profiles and integration of transcriptome and genome …

SG Jammula, AC Katz-Summercorn, X Li, C Linossi… - Gastroenterology, 2020 - Elsevier
… sites that were methylated in normal tissues (mean β-value >0.2). Methylation data was then
… , 31 ) for positive DNA methylation, and discarded CpG sites methylated in fewer than 10% …

Evolving insights on how cytosine methylation affects protein–DNA binding

AC Dantas Machado, T Zhou, S Rao… - Briefings in …, 2015 - academic.oup.com
… Given these complexities, it seems unlikely that the influence of DNA methylation on
protein–DNA binding can be captured in a small set of general rules. Hence, data-driven …