Differential DNA methylation of the genes for amyloid precursor protein, tau, and neurofilaments in human traumatic brain injury

S Abu Hamdeh, DM Ciuculete, D Sarkisyan… - Journal of …, 2021 - liebertpub.com
… the DNA sequence in response to environmental factors. We hypothesized that DNA methylation
… Aggregated tau (neurofibrillary tangles [NFTs]) was widely distributed in the brains of …

Distinct CSF biomarker-associated DNA methylation in Alzheimer's disease and cognitively normal subjects

W Zhang, JI Young, L Gomez, MA Schmidt… - Alzheimer's research & …, 2023 - Springer
… Our study included matched samples of whole blood DNA methylation, CSF Aβ 42 ,
phosphorylated tau 181 (pTau 181 ), and total tau (tTau) biomarkers data, measured on the same …

[HTML][HTML] Independent effect of main components in particulate matter on DNA methylation and DNA methyltransferase: A molecular epidemiology study

Y Wang, T Wang, M Xu, H Yu, C Ding, Z Wang… - Environment …, 2020 - Elsevier
… its component with DNA methylation, and the roles of DNADNA methylation and DNMT3B
expression with elevated PM levels in population. The independent mode of action on DNA

DNA Methylation Analysis Reveals Distinct Patterns in Satellite Cell–Derived Myogenic Progenitor Cells of Subjects with Spastic Cerebral Palsy

KG Robinson, AG Marsh, SK Lee, J Hicks… - Journal of personalized …, 2022 - mdpi.com
DNA methylation patterns can be altered in CP. Here, we examined whether a diagnosis of
spastic CP is associated with intrinsic DNA methylationDNA methylation analyses indicated …

Identification of methylated gene biomarkers in patients with Alzheimer's disease based on machine learning

J Ren, B Zhang, D Wei, Z Zhang - BioMed Research …, 2020 - Wiley Online Library
… AD is characterized with deposition of formation of neurofibrillary tanglesmethylated genes
in the pathology of AD based on the machine learning. We first obtained the DNA methylation

Amyloid-β alters the DNA methylation status of cell-fate genes in an Alzheimer's disease model

N Taher, C McKenzie, R Garrett… - Journal of …, 2014 - content.iospress.com
… Alzheimer’s disease (AD) is characterized by neurofibrillary tangles and extracellular amyloid-…
in DNA methylation in differentiated human neurons with and without Aß treatment. DNA

Stealth technology: how Epstein–Barr virus utilizes DNA methylation to cloak itself from immune detection

Q Tao, KD Robertson - Clinical Immunology, 2003 - Elsevier
… usurped the host cell DNA methylation system and used it in … known about how DNA
methylation regulates both latent and … we might make use of DNA methylation inhibitors to uncloak …

Nucleosomes protect DNA from DNA methylation in vivo and in vitro

M Felle, H Hoffmeister, J Rothammer… - Nucleic acids …, 2011 - academic.oup.com
… To evaluate the effect of positioned nucleosomes on the DNA methylationDNA methylation
events in reconstituted chromatin systems and quantified nucleosomal DNA methylation in …

Dynamics of DNA methylation in aging and Alzheimer's disease

HA Irier, P Jin - DNA and cell biology, 2012 - liebertpub.com
… of DNA methylation in neurodegenerative diseases, with a special focus on DNA methylation
dynamics … DNA methylation dynamics. Genomic cytosine nucleotide (C) is converted to 5-…

Brain DNA methylation patterns in CLDN5 associated with cognitive decline

A Hüls, C Robins, KN Conneely, R Edgar… - Biological …, 2022 - Elsevier
… little signs of amyloid-β and neurofibrillary tangle pathology. … (approximately 0.4) with brain
methylation (15). Thus, there is … brain tissue–based DNA methylation and cognitive trajectory …