The Cross‐Talk between Polyphenols and the Target Enzymes Related to Oxidative Stress‐Induced Thyroid Cancer

S Heydarzadeh, SK Kia, M Zarkesh… - Oxidative Medicine …, 2022 - Wiley Online Library
… research strategy for thyroid cancer pathogenesis and therapy. Despite … cancer models, this
study will discuss the modulation of enzymatic ROS sources by polyphenols in thyroid cancer

NADPH oxidases: new actors in thyroid cancer?

R Ameziane-El-Hassani, M Schlumberger… - Nature Reviews …, 2016 - nature.com
… and function of these enzymes. We focus on their potential role in thyroid cancer, which is …
extension, and both the targeting and function of DUOX enzymes at the plasma membrane …

[HTML][HTML] The role of altered mitochondrial metabolism in thyroid cancer development and mitochondria-targeted thyroid cancer treatment

SA Dabravolski, NG Nikiforov, AD Zhuravlev… - International Journal of …, 2021 - mdpi.com
thyroid carcinogenesis. In this review, we focus on the recent progress in understanding the
molecular mechanisms of thyroid cancer … The key enzymes in these pathways (COX4, NOX4 …

[PDF][PDF] Review of pharmacological inhibition of thyroid cancer metabolism

CD Davidson, FE Carr - J Cancer Metastasis Treat, 2021 - f.oaes.cc
… Glycolytic enzymes and transporters are dysregulated in many forms of thyroid cancer. Bold
text for transporters … Acetyl coa carboxylase: a potential therapeutic target in thyroid cancer. …

Thyroid peroxidase as a dual active site enzyme: Focus on biosynthesis, hormonogenesis and thyroid disorders of autoimmunity and cancer

M Godlewska, PJ Banga - Biochimie, 2019 - Elsevier
… TPO is a key enzyme in thyroid hormone synthesis and target … human cancer, thyroid tumor
tissue and breast cancer differ in TPO expression and isoform composition. In thyroid cancer, …

New molecular targeted therapies in thyroid cancer

A Milano, MG Chiofalo, M Basile, AS de Luna… - Anti-cancer …, 2006 - journals.lww.com
enzymes COX-2 and thromboxane A 2 synthase, an enzyme located downstream from
COX-2, in papillary carcinomas and matching normal tissues to determine the role of this enzyme

Targeted therapy in thyroid cancer: state of the art

L Valerio, L Pieruzzi, C Giani, L Agate, V Bottici… - Clinical oncology, 2017 - Elsevier
targeted treatments. The drugs that have primarily been investigated for the treatment of thyroid
cancer … Tyrosine kinases are enzymes responsible for the control of mitogenic signals via …

[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: progress and opportunities

L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - … (BBA)-Reviews on Cancer, 2023 - Elsevier
… For RR-DTC, ongoing studies using the BRAF enzyme inhibitor are generally conducted
through … Vemurafenib is a BRAF enzyme inhibitor approved for the treatment of melanoma with …

Metabolic alterations of thyroid cancer as potential therapeutic targets

D Ciavardelli, M Bellomo, A Consalvo… - BioMed research …, 2017 - Wiley Online Library
… metabolic alterations of TC and speculate that targeting TC metabolism may improve current
… efficacy of inhibition of enzymes or transporters involved in the metabolic reprogramming of …

Targeted therapy of thyroid cancer

SI Sherman - Biochemical Pharmacology, 2010 - Elsevier
… of several isotypes of HDAC enzymes, valproic acid (VPA) … The successful development
of targeted therapies for cancer requires … of successful targeted therapies for thyroid cancers. …