… Our findings suggest that Smad6 may play a negative regulatory role in rat fracture healing
… healing in their regulation of BMPs and TGF-β. Future studies focused on the up-regulation of …

… One such cue, transforming growth factor β (TGFβ), prominently induces EMT via a group of
… Another aspect is the availability and regulation of receptors and signaling mediators on the …

… Transforming growth factor-β (TGF-β) is an intriguing cytokine exhibiting dual activities in
malignant disease. It is an important mediator … lead to better regulation of TGF-β1 activity [131]. …

… Transforming growth factor β (TGFβ) is the main ligand that … process, TGFβ and its canonical
signaling mediators are tightly … epigenetic regulation related to canonical TGFβ signaling in …

… Finally, there is evidence that Smad3 is a central mediator in the TGF-β1-induced increase
… TGF-β1 plays an essential, regulatory role in the control of colitis. On the other hand, in mice …

… As outlined above, TGF-β is among other polypeptide mediators involved in hepatic …
and a common use of signalling pathways and probably because of up-regulation of TGF-β1 …

… to adequately explain the regulation of differentiation genes by TGF-β signals. In contrast to
… as a signal transducer and direct mediator of transcription in the TGF-β pathway was recently …

… are powerful mediators of tumor … that TGFβ activity is a major obstacle hindering the ability
of radiation to generate an in situ tumor vaccine. Here, we show that antibody-mediated TGFβ …

… (IL-10) and transforming growth factor-β (TGF-β). Type 1 T regulatory (Tr1) cells are defined
by their ability to produce high levels of IL-10 and TGF-β, and these cytokines mediate their …

… effects of TGFβ which may induce … of TGFβ signaling pathways in aging chondrocytes. This
review focuses on the functions of TGFβ in joints and the regulation of its signaling mediators (…