… The transforming growth factor β (TGF-β) family of growth factorscontrol the development …
Work over the past few years has led to the elucidation of a TGF-β signaltransduction network. …

… Transforming growth factor β (TGFβ) … Signaling is modulated by negative-feedback
regulation via inhibitory Smads. We review here the mechanisms of TGFβ signal transduction in …

Smad proteins transduce signals from transforming growth factor-β (TGF-β) superfamily
ligands that regulate cell proliferation, differentiation and death through activation of receptor …

… Transforming growth factor-β (TGFβ) family members are … Dysregulation of TGFβ family
signaling can lead to a plethora … In this review, we focus on TGFβ, a well-characterized family …

Signal transduction by the TGF-β family involves sets of … Smads and transcription factors in
the TGF-β and BMP pathways. A … the TGF-β and BMP pathways segregated from each other. …

… Recent data support the notion that Smads are important intracellular effectors of TGF-β in
immune cells. Here, we review recent advances in TGF-β signal transduction in immune cells. …

… This review summarizes both in vitro and in vivo evidence of TGF-β/BMP-mediated signal
transduction pathways in OA and discusses the future research direction in this regard. …

… In addition, TGF-β itself plays an important role in cancer … , and numerous components of
the signal transduction pathway are tumor … how TGF-β family members signal their effects. …

… TGF-β in physiological and pathological conditions, elaborated TGF-β associated signal
transduction… studies and clinical strategies targeting TGF-β signal transduction to treat diseases. …

… of TGF-β signaling. … signal transduction has been associated with many human diseases,
including cancer and tissue fibrosis [1–3]. TGF-β signaling is initiated by the binding of TGF-β to …