Development of effective therapies for sepsis

M Booke, LD Traber, DL Traber - Critical care medicine, 1995 - journals.lww.com
… Because of this similarity in sensitivity, we believe that these models are not only
appropriate, but ideal to study sepsis and new therapeutic approaches for sepsis, which may be …

The microcirculation as a therapeutic target in the treatment of sepsis and shock

VSK Edul, A Dubin, C Ince - Seminars in respiratory and critical …, 2011 - thieme-connect.com
… conventional and new therapeutic approaches that are successful in modifying the
microcirculation. Current research must determine whether some of these approaches are successful …

The presence of superantigens and complex host responses in severe sepsis may need a broad therapeutic approach

BG Stegmayr - Therapeutic Apheresis, 2001 - Wiley Online Library
septic shock requires the removal or inhibition of several toxins or substances activating the
cascade systems. A broader therapeutic approach … narrow therapeutic approaches which …

New therapeutic approach for the treatment for staphylococcal bacteremia and sepsis

VB Beloborodov - Epidemiology and Infectious Diseases, 2014 - journals.eco-vector.com
approaches to the treatment for bacteremia/sepsis caused by S. aureus, have surprisingly
low conclusiveness and require the optimization of antibiotic therapy… bacteremia and sepsis. …

Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy

AL Vijayan, null Vanimaya, S Ravindran… - Journal of intensive …, 2017 - Springer
… understand the application of PCT in the diagnosis of sepsis, differentiating between microbial
and non-microbial infection cases and determining the therapeutic approaches for sepsis. …

Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis

Z Yan, H Luo, B Xie, T Tian, S Li, Z Chen, J Liu… - Nature …, 2021 - nature.com
… but also provides a potential therapeutic target for sepsis. More … , the therapeutic effect of
TAT-SAM on sepsis was observed … for therapeutic interventions for sepsis could be developed. …

Gases in sepsis: novel mediators and therapeutic targets

Z Zhu, S Chambers, Y Zeng, M Bhatia - International Journal of Molecular …, 2022 - mdpi.com
… paid to developing therapeutic approaches targeting these molecules for sepsis/septic shock,
… Several preliminary studies have identified promising therapeutic strategies for gaseous-…

The hemodynamic derangements in sepsis: implications for treatment strategies

PE Marik, J Varon - Chest, 1998 - Elsevier
… use of novel therapeutic approaches, the mortality associated with the sepsis syndrome has
… with sepsis. Recent studies have failed to demonstrate a global oxygen debt in patients with …

Phagocytosis–inflammation crosstalk in sepsis: new avenues for therapeutic intervention

M Hortová-Kohoutková, F Tidu, M De Zuani, V Šrámek… - Shock, 2020 - journals.lww.com
… little impact on therapeutic approaches in sepsis. As mentioned above, specific
phagocytosis-targeted therapy is not in routine use but some routine approaches influence …

Sepsis roadmap: what we know, what we learned, and where we are going

V Kumar - Clinical Immunology, 2020 - Elsevier
… are in an urgent need for a multi-targeting therapeutic approach for sepsis. … sepsis
pathogenesis, lessons learned, and the future therapeutic/early diagnostic approaches to target …