… Although its roles in CNS pathology are only beginning to be … roles in, a host of CNS disorders
via loss of normal or gain of … therapeutic targets for a wide range of neurological disorders…

… or reducing the effects of CNS disorders. In this review, … therapeutic targets that could be
leveraged to restore the integrity of the BBB concomitant to the treatment of these brain disorders…

… role of leukocyte accumulation during neuroinflammation in CNS disorders [15-21]. Better
… insight into novel or alternative therapeutic approaches to treat inflammatory CNS disorders. …

… These receptors are widely distributed throughout the central nervous system (CNS… CNS.
Neuronal nAChR dysfunction is involved in the pathophysiology of many neurological disorders…

… For each of these transcription factors we review their roles in neuronal cell loss
disorders and the most relevant patents associated with the treatment of CNS disorders. …

… receptor are abundant throughout the whole CNS, and BDNF is a … for therapeutic treatment
of some of CNS disorders. This review aims to correlate the features of some CNS disorders (…

… to be adequately translated into effective therapies, each of the targets holds promise for the
… drug development for CNS disorders, ion channels of enteric neurons are attractive targets. …

… signalling cascades have emerged as potential CNS therapeutic targets, including ERK1,
ERK2, … investigated as a potential therapeutic target for many CNS disorders. Diverse chemical …

… of therapeutic drugs, targeting pathways controlled by these novel proposed genes, may be
developed to treat CNS disorders … recognized spectrum nature of brain disorders [12] and on …

… pathology have demonstrated a promising therapeutic landscape for TrkB inhibitors in the
treatment of various diseases, eg central nervous system (CNS) disorders and several types of …