Many cytokines are very useful therapeutic targets in disease
M Feldmann - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
… Rather, representative examples of the cytokines involved in some forms of cancer and … of
cytokines as therapeutic targets, and the overwhelming message is that “anti-cytokine medicine…
cytokines as therapeutic targets, and the overwhelming message is that “anti-cytokine medicine…
Cytokines as therapeutic targets in SLE
L Rönnblom, KB Elkon - Nature Reviews Rheumatology, 2010 - nature.com
… Many cytokine pathways of importance in the pathogenesis of systemic lupus erythematosus
(SLE) have been identified and clinical trials of biologic agents targeting a number of these …
(SLE) have been identified and clinical trials of biologic agents targeting a number of these …
Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases
S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015 - ASPET
… Cytokines are therefore attractive therapeutic targets in these conditions. Anticytokine therapy
for … Finally, we report on the current state of trials for newer therapeutic targets, focusing …
for … Finally, we report on the current state of trials for newer therapeutic targets, focusing …
Historical review: cytokines as therapeutics and targets of therapeutics
J Vilček, M Feldmann - Trends in pharmacological sciences, 2004 - cell.com
… Cytokine research has spawned the introduction of new therapies that have revolutionized
the treatment of many … the introduction of cytokine and anti-cytokine therapies, with emphasis …
the treatment of many … the introduction of cytokine and anti-cytokine therapies, with emphasis …
Therapeutic antibodies that target inflammatory cytokines in autoimmune diseases
Y Lai, C Dong - International immunology, 2016 - academic.oup.com
… cytokines regulates autoimmune diseases. On the basis of pre-clinical and clinical data, we
specifically discuss the therapeutic rationale for targeting these cytokines … that many new, …
specifically discuss the therapeutic rationale for targeting these cytokines … that many new, …
Cytokines as therapeutic drugs
H Schooltink, S Rose-John - Journal of interferon & cytokine …, 2002 - liebertpub.com
… 1A), describes the fact that many cytokines exhibit different … Many activities are shared
between different cytokines (Fig. 1B), an attribute called redundancy. Blocking one cytokine …
between different cytokines (Fig. 1B), an attribute called redundancy. Blocking one cytokine …
Cytokines as therapeutic targets for osteoarthritis
CJ Malemud - BioDrugs, 2004 - Springer
… were not often co-expressed in cartilage, so that the potential for local cytokine inhibition …
[2] MMPs are capable of degrading many of the ECM proteins including proteoglycans, …
[2] MMPs are capable of degrading many of the ECM proteins including proteoglycans, …
Cytokines as a therapeutic target for allergic diseases: a complex picture
JA Woodfolk - Current Pharmaceutical Design, 2006 - ingentaconnect.com
… the cytokine network in allergic disease. This article highlights the challenges of dissecting
the role of individual cytokines in … therapies which target Th1, Th2 and regulatory cytokines on …
the role of individual cytokines in … therapies which target Th1, Th2 and regulatory cytokines on …
[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets
… cytokines in atherosclerosis together with therapeutic … Many cytokines are expressed in
atherosclerotic plaques and all cells involved in the disease are capable of producing cytokines …
atherosclerotic plaques and all cells involved in the disease are capable of producing cytokines …
Immunopathobiology and therapeutic targets related to cytokines in liver diseases
… Th1 cells can produce many cytokines that play important roles in the pathogenesis of liver
diseases (Fig. 1). Among them, both IFN-γ and TNFα have been extensively investigated over …
diseases (Fig. 1). Among them, both IFN-γ and TNFα have been extensively investigated over …
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