Inflammatory cytokines and chemokines as therapeutic targets in heart failure
A Hanna, NG Frangogiannis - Cardiovascular Drugs and Therapy, 2020 - Springer
… an attractive therapeutic target in many conditions associated … therapy for patients with
moderate to severe rheumatoid arthritis and temporal arteritis, and for the treatment of the cytokine …
moderate to severe rheumatoid arthritis and temporal arteritis, and for the treatment of the cytokine …
Cytokines in sepsis: potent immunoregulators and potential therapeutic targets—an updated view
W Schulte, J Bernhagen, R Bucala - Mediators of inflammation, 2013 - Wiley Online Library
… IL-10 is a 35-kDa homodimeric cytokine that is produced by many types of immune cells,
such as monocytes, macrophages, B and T lymphocytes, and NK cells [87]. Functional studies …
such as monocytes, macrophages, B and T lymphocytes, and NK cells [87]. Functional studies …
Historical insights into cytokines
CA Dinarello - European journal of immunology, 2007 - Wiley Online Library
… with overlapping functions and many still unexplored. Also discussed in this overview …
cytokines as therapeutic targets. A recent advance in the field has been that of differential cytokine …
cytokines as therapeutic targets. A recent advance in the field has been that of differential cytokine …
Cytokines as therapeutic targets for cardio-and cerebrovascular diseases
… Mainly involved in fibrotic processes, TGF-β targets several cell types many of which are
deeply involved with high cardiovascular relevance: monocytes/macrophages, neutrophils, …
deeply involved with high cardiovascular relevance: monocytes/macrophages, neutrophils, …
Cytokines as therapeutic targets to reduce cardiovascular risk in chronic inflammation
AM Miller, IB McInnes - Current pharmaceutical design, 2011 - ingentaconnect.com
… cytokine–related signaling pathways in inflammatory diseases has prompted the development
of many therapeutic … In this review we will focus on the role of pro-inflammatory cytokines …
of many therapeutic … In this review we will focus on the role of pro-inflammatory cytokines …
IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
N Unver, F McAllister - Cytokine & growth factor reviews, 2018 - Elsevier
… Chemoprevention targets many steps including tumor initiation, promotion and progression.
… the mechanism of Quercetin, a compound found in many plant-based foods, which has been …
… the mechanism of Quercetin, a compound found in many plant-based foods, which has been …
An overview of cytokines and cytokine antagonists as therapeutic agents
RP Donnelly, HA Young… - Annals of the New York …, 2009 - Wiley Online Library
… , many novel cytokines have been discovered during the last ten years, and it is reasonable
to predict that at least some of these cytokines will provide useful therapeutic targets for …
to predict that at least some of these cytokines will provide useful therapeutic targets for …
Cytokines and anti-cytokines as therapeutics—An update
V Tayal, BS Kalra - European journal of pharmacology, 2008 - Elsevier
… in the area of cytokines and their therapeutic targets, the two major therapeutic modalities
being … Cytokines serve many functions in the body such as mediating and regulating immunity, …
being … Cytokines serve many functions in the body such as mediating and regulating immunity, …
Cytokines in Sjögren's syndrome: potential therapeutic targets
N Roescher, PP Tak, GG Illei - Annals of the rheumatic diseases, 2010 - ard.bmj.com
… , which is not justified for many SS patients. Because the … cytokine-based therapy for SS
patients, would be the local delivery of cytokines or their inhibitors, for example by gene therapy, …
patients, would be the local delivery of cytokines or their inhibitors, for example by gene therapy, …
Cytokines as therapeutic targets in skin inflammation
… also a considerable problem for many psoriasis sufferers. Furthermore, … Many of the available
topical treatment options are time … of anti-cytokine biologics to our therapeutic portfolio has …
topical treatment options are time … of anti-cytokine biologics to our therapeutic portfolio has …