Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases
S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015 - ASPET
… application of anticytokine therapies for other inflammatory diseases, particularly within the
… across diseases. Finally, we report on the current state of trials for newer therapeutic targets, …
… across diseases. Finally, we report on the current state of trials for newer therapeutic targets, …
miRNAs as therapeutic targets in inflammatory disease
Q Lu, R Wu, M Zhao, A Garcia-Gomez… - Trends in pharmacological …, 2019 - cell.com
… therapeutic targets in these diseases. In this review, by selecting several examples of
inflammatory diseases, … of certain miRNAs in these diseases, their targets, and the importance of …
inflammatory diseases, … of certain miRNAs in these diseases, their targets, and the importance of …
The IL23/Th17 pathway as a therapeutic target in chronic inflammatory diseases
É Toussirot - … (Formerly Current Drug Targets-Inflammation & …, 2012 - ingentaconnect.com
… inflammatory diseases such as chronic joint diseases, inflammatory bowel diseases and
demyelinating diseases … as a relevant therapeutic target in autoimmune driven diseases, and …
demyelinating diseases … as a relevant therapeutic target in autoimmune driven diseases, and …
Macrophage migration inhibitory factor: a therapeutic target across inflammatory diseases
… a severe systemic autoimmune disease and agedependent inflammatory damage to end …
which paralleled the upregulation of other key inflammatory cytokines and chemokines such as …
which paralleled the upregulation of other key inflammatory cytokines and chemokines such as …
Toll-like receptors: promising therapeutic targets for inflammatory diseases
… diseases. In this review, we discuss the emerging role of TLRs in the pathogenesis of
inflammatory diseases and how targeting of TLRs offers a promising therapeutic strategy for the …
inflammatory diseases and how targeting of TLRs offers a promising therapeutic strategy for the …
[PDF][PDF] Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets
JP Pelletier, J Martel‐Pelletier… - Arthritis & Rheumatism …, 2001 - stem-art.com
… that have the potential to become therapeutic targets. These pathways can be modified to
effectively retard the progression of the disease. A number of such new agents, referred to as …
effectively retard the progression of the disease. A number of such new agents, referred to as …
p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases
S Kumar, J Boehm, JC Lee - Nature reviews Drug discovery, 2003 - nature.com
… , along with other therapeutic … therapeutic targets for rheumatoid arthritis. The availability
of p38 MAPK inhibitors such as SB-203580 has led to their widespread use in many different in …
of p38 MAPK inhibitors such as SB-203580 has led to their widespread use in many different in …
Novel therapeutic targets for inflammatory bowel disease
M Argollo, G Fiorino, P Hindryckx, L Peyrin-Biroulet… - Journal of …, 2017 - Elsevier
… Pipeline of new drugs under development and diverse therapeutic targets for the treatment
of IBD. IBD, inflammatory bowel diseases; SMD, small molecule drug; pre-clinic: testing of …
of IBD. IBD, inflammatory bowel diseases; SMD, small molecule drug; pre-clinic: testing of …
TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
M Feldmann, RN Maini - Nature medicine, 2003 - nature.com
… of human autoimmune diseases, an interest I had acquired at WEHI. In these diseases, …
I started by analyzing thyroid diseases, and from this study in the early 1980s I realized that …
I started by analyzing thyroid diseases, and from this study in the early 1980s I realized that …
New therapeutic target in inflammatory disease: macrophage migration inhibitory factor
EF Morand - Internal medicine journal, 2005 - Wiley Online Library
… inflammatory diseases rather than being disease-specific. This implies the need to identify
a therapeutic target which participates in the range of mechanisms operative in inflammation …
a therapeutic target which participates in the range of mechanisms operative in inflammation …
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