Platelet receptors as therapeutic targets: past, present and future

J Jamasbi, K Ayabe, S Goto… - Thrombosis and …, 2017 - thieme-connect.com
… The present concise review aims to cover current and future developments of anti-platelet
drugs interfering with the interaction of von Willebrand factor (VWF) with glycoprotein (GP) Ibα, …

Therapeutic targets in sepsis: past, present, and future

EJ Seeley, GR Bernard - Clinics in Chest Medicine, 2016 - chestmed.theclinics.com
… of sepsis therapy (Table 1) and identifies possible causes for why rational therapies failed
in human trials. In addition, this article examines potential future sepsis targets and considers …

Current and future therapeutic targets of rheumatoid arthritis

Y Ming Di, ZW Zhou, C Guang Li… - … (Formerly Current …, 2011 - ingentaconnect.com
… to identify current therapeutic targets for RA based on data from the literature and drug target
related … This article aims to identify current therapeutic targets for RA based on data from the …

Therapeutic targets: progress of their exploration and investigation of their characteristics

CJ Zheng, LY Han, CW Yap, ZL Ji, ZW Cao… - Pharmacological …, 2006 - ASPET
… in the exploration of therapeutic targets for the discovery of drugs … therapeutic targets and
to investigate the characteristics of these targets for providing useful clues to search new targets

Therapeutics of Alzheimer's disease: Past, present and future

R Anand, KD Gill, AA Mahdi - Neuropharmacology, 2014 - Elsevier
… , which could hold the key to treatment of AD in the near future. Several putative drugs have
… from the past mistakes. The current rationales and targets evaluated for therapeutic benefit in …

Past, present, and future technologies for oral delivery of therapeutic proteins

R Singh, S Singh, JW Lillard - Journal of pharmaceutical sciences, 2008 - Elsevier
… proteins being investigated for therapeutic applications has increased. Success of these
new therapeutics hinges on efficient DDSs that allow drug access to their target site(s) at the …

Current and emerging therapeutic targets for IBD

MF Neurath - Nature Reviews Gastroenterology & Hepatology, 2017 - nature.com
… overview about current and future therapeutic approaches for IBD therapy. Furthermore,
potential … therapeutic approaches and their implications for clinical therapy in IBD are discussed. …

Targeted α-therapy: past, present, future?

MW Brechbiel - Dalton Transactions, 2007 - pubs.rsc.org
Monoclonal antibodies have become a viable strategy for the delivery of therapeutic, … to
making radioimmunotherapy (RIT) a standard therapeutic modality due to the fundamental and …

Molecular targeted therapies in hepatocellular carcinoma: past, present and future

M Stotz, A Gerger, J Haybaeck, T Kiesslich… - Anticancer …, 2015 - ar.iiarjournals.org
… the limited therapeutic options available and an ongoing tendency for late diagnosis,
highlighting the importance of research to identify novel prognostic and therapeutic targets in HCC. …

[HTML][HTML] Heparin binding proteins as therapeutic target: an historical account and current trends

G Ghiselli - Medicines, 2019 - mdpi.com
… the text we provide examples from past and present literature concerning angiogenic factors
and … site of proteins as a means to generate a new class of biologics of therapeutic interest. …