Background : Guidelines strongly recommend patients with heart failure with reduced ejection
fraction (HFrEF) be treated with multiple medications proven to improve clinical outcomes, …

… and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment
of acute and chronic heart failure of the … of the Heart Failure Association (HFA) of the ESC.  …

… heart failure has led to a reduction in recent years in mortality and frequency of hospitalizations
in patients with heart failure and reduced ejection fraction … therapy have improved patients…

… Guidelines recommend that patients with heart failure with reduced ejection fraction (HFrEF)
have medical therapy titrated to target doses derived from clinical trials, as tolerated. The …

… several therapies for the management of heart failure … in patients with heart failure with
reduced ejection fraction (HFrEF) and in patients with heart failure with preserved ejection fraction …

… The burden of heart failure with preserved ejection fraction (HFpEF) is considerable and is
… no approved therapies available for reducing mortality or hospitalizations for these patients. …

… recommended initiating therapy in patients with heart failure and reduced ejection fraction
(… , with cautious up-titration of each treatment. It remains unclear whether this historical …

… for the large majority of patients with heart failure with reduced ejection fraction (HFrEF) who
are hemodynamically stable at presentation and initially treated with IV diuretic therapy, pre-…

… Among patients with heart failure with reduced ejection fraction, left ventricular ejection fraction
… Patients with heart failure with improved ejection fraction (HFiEF) have better prognosis …

… heart failure (HF) trials were frequently neutral in heart failure with normal left ventricular
ejection fraction … positive in heart failure with reduced left ventricular ejection fraction (HFREF). …