The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3′-fluoro-3′-deoxythymidine in human B-lymphoblast cells
DA Plotnik, LJ McLaughlin, J Chan… - Nuclear medicine and …, 2011 - Elsevier
… transporter-1 (hENT1) as a modifier of 3′-fluoro-3′-deoxythymidine (FLT) uptake … in
thymidine kinase 1 (TK1) to study how metabolism and nucleoside transport influence FLT uptake …
thymidine kinase 1 (TK1) to study how metabolism and nucleoside transport influence FLT uptake …
Cytotoxicity and cellular uptake of pyrimidine nucleosides for imaging herpes simplex type-1 thymidine kinase (HSV-1 TK) expression in mammalian cells
KW Morin, W Duan, L Xu, A Zhou, S Moharram… - Nuclear medicine and …, 2004 - Elsevier
… and nucleoside transport rates of the six nucleosides tested … In summary, these nucleosides
are unpredictably cytotoxic to … expression characteristic; their uptake by cells engineered to …
are unpredictably cytotoxic to … expression characteristic; their uptake by cells engineered to …
Correlation of 18F-FLT uptake with equilibrative nucleoside transporter-1 and thymidine kinase-1 expressions in gastrointestinal cancer
R Kameyama, Y Yamamoto, K Izuishi… - Nuclear medicine …, 2011 - journals.lww.com
… that ENT1 activity and FLT uptake were not related. … nucleoside transporter-1 (ENT1) [ 4–6
]. This tracer is trapped within the cytosol after being monophosphorylated by thymidine kinase…
]. This tracer is trapped within the cytosol after being monophosphorylated by thymidine kinase…
The association of thymidine kinase activity and thymidine transport in Escherichia coli
DK Dube, MSZ Horwitz, LA Loeb - Gene, 1991 - Elsevier
… uptake of exogenous nucleosides is suggested by its evolutionary conservation. Furthermore,
the selective uptake … of a nucleotidebinding domain in HSV-1 thymidine kinase: effects on …
the selective uptake … of a nucleotidebinding domain in HSV-1 thymidine kinase: effects on …
Thymidine uptake and utilization in Escherichia coli: a new gene controlling nucleoside transport
M McKeown, M Kahn, P Hanawalt - Journal of Bacteriology, 1976 - Am Soc Microbiol
… examine a mutant lacking thymidine kinase. There may be other nucleoside-specific proteins
… Finally, since our measurements of uptake and accumulation of thymidine are dependent …
… Finally, since our measurements of uptake and accumulation of thymidine are dependent …
Effects of thymidylate synthase inhibition on thymidine kinase activity and nucleoside transporter expression
J Pressacco, B Mitrovski, C Erlichman, DW Hedley - Cancer research, 1995 - AACR
… from the extracellular fluid and phosphorylation by thymidine kinase in the salvage pathway.
… to increase nucleoside analogue uptake, this has been attributed to effects in kinases(31). …
… to increase nucleoside analogue uptake, this has been attributed to effects in kinases(31). …
Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1
PK Bae, JH Kim, HS Kim, IK Chung, SG Paik, CK Lee - Antiviral research, 2006 - Elsevier
… thymidine (Thd) kinase (TK) of herpes simplex virus type 1 (HSV-1) on the intracellular uptake
and anabolism of nucleosides … The cellular uptake of thymidine was highly dependent on …
and anabolism of nucleosides … The cellular uptake of thymidine was highly dependent on …
Thymidine uptake, thymidine incorporation, and thymidine kinase activity in marine bacterium isolates
WH Jeffrey, JH Paul - Applied and environmental microbiology, 1990 - Am Soc Microbiol
… Thymidine uptake and incorporation and thymidine kinase … of thymidine incorporation
demonstrated thymidine uptake as … of thymidine kinase and a nonspecific nucleoside kinase which …
demonstrated thymidine uptake as … of thymidine kinase and a nonspecific nucleoside kinase which …
Cytofluorometric assay for the determination of thymidine uptake and phosphorylation in living cells
M Hengstschläuger, E Wawra - Cytometry: The Journal of the …, 1993 - Wiley Online Library
… The cellular uptake of thymidine and its phosphorylation are … thymidine analogues reflects
the activity of thymidine kinase (… /tk+ cells offering our fluorescent nucleosides as substrate. In …
the activity of thymidine kinase (… /tk+ cells offering our fluorescent nucleosides as substrate. In …
[HTML][HTML] Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA
K Sakamoto, T Yokogawa, H Ueno… - International …, 2015 - spandidos-publications.com
… nucleoside or nucleoside analog to initiate uptake. At appropriate times, 160-μl aliquots
of cell suspension were withdrawn, and cells were separated by centrifugation through a …
of cell suspension were withdrawn, and cells were separated by centrifugation through a …
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