… Over the last 2 years, substantial work has also described BRAF mutations in thyroid cancer,
… As these are rare thyroid tumors, BRAF mutation in these tumors has generally not been …

… oncogenic activation of the mutated BRAF kinase (33, 43). A few other … BRAF mutants are
only rarely found in thyroid cancer, such as the BRAF K601E (44), AKAP9-BRAF (45), BRAF …

… Papillary thyroid cancer (PTC) is a common endocrine malignancy that frequently harbors
the oncogenic T1799A BRAF mutation. As a novel prognostic molecular marker, this mutation …

… neck cancers but not in bladder, cervical, or prostate cancers. Our data suggest that activating
BRAF mutations may be an important event in the development of papillary thyroid cancer. …

… is the most frequent genetic alteration in papillary thyroid carcinomas (PTCs) that are 80–90%
of all thyroid cancers. We evaluated the relationship between BRAF (V600E) and tumor, …

… was significantly associated with increased cancer-related … not independent of tumor features,
how to use BRAF V600E to … and therapeutic implications of BRAF V600E status in PTC. …

… the presence of a BRAF V600E mutation in thyroid cancer is associated with an aggressive
… thyroid tumors, we found 1 FTC that had a BRAF V600E mutation. Because of this, the …

… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) … BRAF mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid …

… Kaplan-Meier survival curves of effect of BRAF V600E mutation status on disease
recurrence–free probability in patients with various types of papillary thyroid cancer (PTC). …

… No mutations were found in KRAS or HRAS. Our results suggest that BRAF mutations
may play a critical role in the carcinogenesis of papillary carcinoma of the thyroid. …