[HTML][HTML] Armed and ready: transcriptional regulation of tissue-resident memory CD8 T cells

FM Behr, A Chuwonpad, R Stark… - Frontiers in …, 2018 - frontiersin.org
… EM cells, a fourth subset of memory CD8 T cells, tissue-resident memory CD8 T (T RM ) cells…
circulating memory populations, T RM cells permanently reside within the peripheral tissues

[HTML][HTML] Tissue-resident memory T cells

JM Schenkel, D Masopust - Immunity, 2014 - cell.com
… receptors by human memory CD8 + and CD4 + T cells led to the conceptualization that …
It should be noted that the existing literature is more developed for CD8 + rather than CD4 + …

Tissue-resident memory T cells: local specialists in immune defence

SN Mueller, LK Mackay - Nature Reviews Immunology, 2016 - nature.com
… , that memory CD8 + T cells can remain in tissues after infection … memory T cell subsets in
tissues and led to the discovery that … As tissue residency is best described for memory CD8 + T …

CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways

AN Wein, SR McMaster, S Takamura… - Journal of Experimental …, 2019 - rupress.org
Resident memory T cells (T RM cells) are an important first-line defense against respiratory …
CD8 T RM cells to the airways. The absence of CXCR6 significantly decreases airway CD8 T …

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

LK Mackay, A Rahimpour, JZ Ma, N Collins… - Nature …, 2013 - nature.com
… Those are called 'tissue-resident memory T cells' (T RM cells); the best characterized are
CD8 + memory T cells that bear the α-chain (CD103) of the integrin α E β 7 together with the …

The molecular signature of tissue resident memory CD8 T cells isolated from the brain

LM Wakim, A Woodward-Davis, R Liu, Y Hu… - The Journal of …, 2012 - journals.aai.org
Tissue resident memory (Trm) CD8 T cells represent a newly described memory T cell
population. We have previously characterized a population of Trm cells that persists within the …

Transcriptional programming of tissue-resident memory CD8+ T cells

JJ Milner, AW Goldrath - Current opinion in immunology, 2018 - Elsevier
Memory CD8 + T cells can be broadly segregated into three distinct subsets: central memory
(T CM ), effector memory (T EM ), and tissue… activities of all three memory CD8 + T cell …

[HTML][HTML] Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

DJ Topham, EC Reilly - Frontiers in immunology, 2018 - frontiersin.org
Tissue-resident memory CD8 + T cells are an important first line of defense from … tissues,
such as the mucosal tissues of the respiratory, digestive, and urogenital tracts. This memory T …

Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments

JT Crowl, M Heeg, A Ferry, JJ Milner, KD Omilusik… - Nature …, 2022 - nature.com
… T RM cells share characteristics with circulating effector and memory CD8 + T cells,
including expression of inflammatory cytokines and cytolytic molecules, sustained lifespan and …

[HTML][HTML] The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues

L Kok, D Masopust, TN Schumacher - Nature Reviews Immunology, 2022 - nature.com
CD8 + tissue resident memory T cells (T RM cells) are essential for immune defence against
pathogens and malignancies, and the molecular processes that lead to T RM cell formation …