Tissue-resident memory T cells in cancer immunosurveillance

SL Park, T Gebhardt, LK Mackay - Trends in immunology, 2019 - cell.com
… The memory CD8 + T cell compartment is comprised of both circulating and resident subsets…
Tissue-resident memory CD8 + T cells (T RM ) reside permanently in peripheral organs (…

Tissue-resident memory T cells in tumor immunity and immunotherapy

K Okła, DL Farber, W Zou - Journal of Experimental Medicine, 2021 - rupress.org
… Blimp-1 rather than Hobit drives the formation of tissue-resident memory CD8CD8 + resident
memory T cells shows tissue-autonomous recall responses that amplify secondary memory

Tissue-resident memory T cells at the center of immunity to solid tumors

D Amsen, KPJM van Gisbergen, P Hombrink… - Nature …, 2018 - nature.com
… CD4 + or CD8 + . They reside in epithelia, connective tissues, neuronal tissue, muscle and
… The defining characteristic of all T RM cells is commitment to their tissue of residence. This …

Tissue-resident memory CD8+ T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells

E Menares, F Gálvez-Cancino… - Nature …, 2019 - nature.com
… and non-lymphoid tissues 5 . In contrast to these circulating subsets, tissue-resident memory
CD8 + T (Trm) cells stably reside in lymphoid and non-lymphoid tissues where they provide …

Severity of sepsis determines the degree of impairment observed in circulatory and tissue-resident memory CD8 T cell populations

SJ Moioffer, DB Danahy, S van de Wall… - The Journal of …, 2021 - journals.aai.org
… , the relative susceptibility of memory CD8 T cell … memory CD8 T cells (T CIRCM), moderate
sepsis (0–10% mortality) does not result in numerical decline of CD8 tissue-resident memory

Human intrahepatic CD69+ CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity

F Stelma, A de Niet, MJ Sinnige, KA van Dort… - Scientific reports, 2017 - nature.com
… In this study we have for the first time in man characterized a population of CD69 + CD8+ T
cells with a tissue resident-like phenotype which is abundantly present in the liver, but not in …

[HTML][HTML] Relevance of tissue-resident memory CD8 T cells in the onset of Parkinson's disease and examination of its possible etiologies: infectious or autoimmune?

O de Fàbregues, M Sellés, D Ramos-Vicente… - Neurobiology of …, 2023 - Elsevier
… nigra, suggesting a relevant role for CD8 T cells in the onset of … will discuss the role of
tissue-resident memory CD8 T cells in … genetic factors can affect the CD8 T cell immune response …

[HTML][HTML] Intrinsic 4-1BB signals are indispensable for the establishment of an influenza-specific tissue-resident memory CD8 T-cell population in the lung

AC Zhou, LE Wagar, ME Wortzman, TH Watts - Mucosal Immunology, 2017 - Elsevier
… as on 4-1BB on the CD8 T cells. … resident Trm population. These findings establish both
endogenous and supraphysiological 4-1BBL as a critical regulator of lung-resident memory CD8

[HTML][HTML] Tissue resident memory T cells in the respiratory tract

MZM Zheng, LM Wakim - Mucosal immunology, 2022 - Elsevier
… is warranted when selecting these vectors as the route of administration and/or the inflammatory
milieu evoked by different vaccine vectors can influence the localization of memory CD8

CD103+ CD8 T Cells in the Toxoplasma-Infected Brain Exhibit a Tissue-Resident Memory Transcriptional Profile

TA Landrith, S Sureshchandra, A Rivera… - Frontiers in …, 2017 - frontiersin.org
… Here, in the context of chronic Toxoplasma gondii infection, we demonstrate that a population
of CD8 T cells exhibiting a tissue-resident memory (T RM ) phenotype accumulates within …