… as measured by cytogenetic response is an important … -ABL transcript levels can predict
chromosomal response. Residual … BCR-ABL and total ABL transcripts were measured in 486 …

… achieved complete cytogenetic response (… transcript levels in imatinib-treated CML patients
after achieving CCyR and showed that the kinetic pattern of the BCR-ABL transcript level …

… rates in the four molecular response categories (excluding … patients who achieved BCR-ABL
transcripts of 0.1% to 1% on … used different BCR-ABL transcript levels that may have been …

… transcript levels to predict cytogenetic relapse by monitoring the BCR-ABL transcript levels
in … analyses seemed to predict for loss of cytogenetic response but the reduction of BCR-ABL …

… cytogenetic response referred to reduction of Ph-positive cells to 1%–35%. A major cytogenetic
response … A major molecular response was defined as BCR-ABL/ABL transcript levels <…

… We investigated the cytogenetic adaptive response of human … dose influences subsequent
gene transcript expression in … Our findings of increased transcript levels in a large number …

… The primary endpoint was MMR at 12 months as defined by a BCR-ABL transcript level ≤
0.1% (IS) on peripheral blood qRT-PCR. Rates of MMR at 12 months were significantly higher …

… Early reduction of BCR-ABL mRNA transcript levels predicts cytogenetic response in chronic
phase CML patients treated with imatinib after failure of interferon alpha. Leukemia 2002; 16…

… transcripts to evaluate the residual disease burden in patients who attained a complete
cytogenetic response (… transcript levels to predict cytogenetic relapse by monitoring the BCR-ABL …

… in the transcript level that predicted for loss of cytogenetic response and progression to …
Because all patients in CCyR who lose their response will have a rise in the transcript levels, we …