… The first is that addressing the translational challenge … is the translational dilemma that
faces biomedical research, and the reason for the development of Translational Systems Biology. …

… This is termed “dynamic knowledge representation.” Agent-based … suited for biomedical
dynamic knowledge representation. Agent-… Translational systems biology using an agentbased …

… While not providing an environment for formal ontology development and evaluation
such as Protege [28], BioXM allows ontologies to be used for knowledge representation and …

… partitioned knowledge can be represented dynamically to … translational goal.3, 4 More
specifically, computer modeling can be seen as a means of dynamic knowledge representation …

… -based modeling and dynamic knowledge representation for hypothesis verification. We
suggest that one of the primary roles of dynamic knowledge representation is exactly this type of …

… share, critique, and evolve the knowledge represented in these conceptual models, particularly
… Effective translational methodologies for knowledge representation need to move both “…

… -based modeling and dynamic knowledge representation for hypothesis verification. We
suggest that one of the primary roles of dynamic knowledge representation is exactly this type of …

… as means for hypothesis instantiation, dynamic knowledge representation, and as proof-of-concept
tools for core translational systems biology applications such as in silico clinical trials …

… This question led to the use of ABM as a knowledge representation tool, constructed by …
dynamics of sepsis. The first of these was whether the anti-inflammatory response represented a …

… translational bioinformatics and systems biology approaches in support of the development
of personalized, systems, and dynamical … for finding effective biomarkers and understanding …