MicroRNAs are involved in cervical cancer development, progression, clinical outcome and improvement treatment response

V GONzáLEz-QuINTANA… - Oncology …, 2016 - spandidos-publications.com
… by which the neuroendocrine macro-environment affected cervical tumor growth, invasion
and therapy resistance, while showing that miR-145 served as a target for CC therapy (36). …

Molecular markers to predict prognosis and treatment response in uterine cervical cancer

M Fleischmann, G Chatzikonstantinou, E Fokas… - Cancers, 2021 - mdpi.com
… risk of cervical cancer development [78]. Furthermore, variants of major histocompatibility
complex (MHC) alleles are associated with increased risk of persistent HPV infection and …

Cervical cancer

SE Waggoner - The lancet, 2003 - thelancet.com
treatment of cervical cancer. Although this cancer poses a far greater health concern in less
developed … The primary cause in development of cervical cancer is human papillomavirus (…

Significance of multiple HPV infection in cervical cancer patients and its impact on treatment response

R Munagala, MG Donà, SN Rai… - International …, 2009 - spandidos-publications.com
… to carcinogenesis and tumor progression predominantly … development of cervical neoplasia.
It is now accepted that HPV may be necessary but not sufficient to cause of cervical cancer

Targeted treatments for cervical cancer: a review

O Peralta-Zaragoza, VH Bermúdez-Morales… - … and therapy, 2012 - Taylor & Francis
… , perturbation of antitumor immune response, alteration of gene … targets for the treatment of
cervical cancer associated with HPV … therapy strategies against cervical cancer development. …

Breaking the DNA damage response to improve cervical cancer treatment

HW Wieringa, AGJ van der Zee, EGE de Vries… - Cancer treatment …, 2016 - Elsevier
… This is of clear importance in the context of cervical cancer, and studies with recently
developed ATR inhibitors, combined with platin-based chemoradiotherapy are eagerly awaited. …

Modulating the DNA damage response to improve treatment response in cervical cancer

LH Cossar, AG Schache, JM Risk, JJ Sacco, NJ Jones… - Clinical Oncology, 2017 - Elsevier
Therapeutic modulation of the DDR is an attractive strategy to increase treatment response
… knowledge surrounding the development of such therapies for cervical cancer in the context …

Cervical cancer: Biomarkers for diagnosis and treatment

S Dasari, R Wudayagiri, L Valluru - Clinica chimica acta, 2015 - Elsevier
… HPV DNA is the only molecular marker developed for the diagnosis of cervical cancer.
Molecular abnormalities such as chromosomal anomalies, DNA mutations, cell cycle check points…

Key molecular events in cervical cancer development

SD Balasubramaniam, V Balakrishnan, CE Oon… - Medicina, 2019 - mdpi.com
Cervical cancer is the fourth most common cancer among … aetiology for the development of
cervical cancer. Infection by high… cervical epithelial cells are key early events in the neoplastic …

Cervical cancer: development of targeted therapies beyond molecular pathogenesis

J Knoff, B Yang, CF Hung, TC Wu - Current obstetrics and gynecology …, 2014 - Springer
… E6 and E7 proteins inactivate and degrade tumor suppressors p53 and … progression. HPV
E6 and E7 antigens are ideal targets for the development of therapies for cervical cancer and …