[HTML][HTML] A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - … journal of cancer, 2017 - nature.com
… NCT01024413) comparing erlotinib with gefitinib for patients with exon 21 mutations. The …
trial by the appropriate independent ethics committees at the Guangdong Lung Cancer Institute…

Effect of erlotinib plus bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 …

TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
… next clinical trial. A phase 1/2 clinical trial that investigated the combination of erlotinib and
… A phase 3 clinical trial compared erlotinib alone with erlotinib plus bevacizumab in patients …

Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non–small-cell lung cancer (RADIANT): A randomized, double-blind, phase III trial

K Kelly, NK Altorki, WEE Eberhardt… - Journal of Clinical …, 2015 - escholarship.org
… Epidermal growth factor receptor (EGFR) –tyrosine kinase inhibitors have proven efficacy
in advanced non–small-cell lung cancer (NSCLC). We hypothesized that erlotinib would be …

Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study

F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
… Symptom improvement in lung cancer patients treated with erlotinib: quality of life
analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. …

[HTML][HTML] Erlotinib in previously treated non–small-cell lung cancer

FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
… phase 2 trial of erlotinib among previously treated patients with non–small-cell lung cancer
in … For this reason, the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) …

Erlotinib (Tarceva): an update on the clinical trial program

RS Herbst - Seminars in oncology, 2003 - Elsevier
… Phase III trials with erlotinib in non-small cell lung cancer and pancreatic cancer are in
progress, as are a range of studies in various indications designed to optimize the use of erlotinib

Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non–small-cell lung cancer

DR Spigel, HA Burris III, FA Greco… - Journal of clinical …, 2011 - ascopubs.org
… shown preliminary activity in non–small-cell lung cancer (NSCLC). Patients with advanced
NSCLC were treated with erlotinib with or without sorafenib in this multicenter phase II trial. …

[HTML][HTML] Erlotinib in lung cancer—molecular and clinical predictors of outcome

MS Tsao, A Sakurada, JC Cutz, CQ Zhu… - … England Journal of …, 2005 - Mass Medical Soc
trial that compared erlotinib with a placebo for non–small-cell lung cancer demonstrated a
survival benefit for erlotinib… in this trial to investigate whether responsiveness to erlotinib and …

Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised …

MC Garassino, O Martelli, M Broggini, G Farina… - The lancet …, 2013 - thelancet.com
… Thus, we did the TArceva Italian Lung Optimization tRial (TAILOR), to compare erlotinib
with docetaxel in patients who failed first-line platinum-based chemotherapy and who had the …

Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non–small-cell lung cancer

TSK Mok, YL Wu, CJ Yu, C Zhou, YM Chen… - Journal of Clinical …, 2009 - ascopubs.org
… in four randomized phase III trials. In these studies, concurrent administration of erlotinib or
gefitinib with … of docetaxel or pemetrexed followed by erlotinib resulting in promising activity. …