… and on the regulation of tumour cell-cell adhesion and … cancer cells and the tumour
microenvironment. In this review, we summarize the roles of glycan alterations in tumour …

… This Review describes how glycans affect and regulate the genesis and progression of cancer.
… glycosylation regulates the colon cancer stem cell compartment and tumour progression …

… glycosylation during all steps of tumour progression, and it is well established that glycans
regulate tumour … Aberrant glycosylation is frequently cited as a hallmark of cancer [11–15], but …

… Although altered glycosylation has been detected in human cancer cells decades ago, …
glycosylation and its role in tumour progression. Many proteins, which are heavily glycosylated, ie …

… Cancer being a cellular disease, … and cancer progression. The present review summarizes
various studies that depicted correlation of glycosylation with tumor initiation, progression and …

… to be breast cancer specific O-glycosylation changes in terms of the corebased structures
synthesised by cancer cell lines. Instead, cell linespecific patterns of glycosylation were seen. …

… cancer suggests that further studies may assist both in determining their role in every step of
tumour progression… Detection of the altered glycans in serum tumour glycoproteins could be …

… This can be achieved by mimicking the glycosylation patterns of healthy immune cells …
cancer stemness. While they could be expected to work in concert to promote tumour progression, …

… In this sense, aberrant in vivo patterns of tumour cell glycosylation may represent a hindrance
underlying limited clinical activity of pre-clinically validated mAbs, by masking or hiding …

… Alterations in glycosylation appear to not only directly impact cell … progression, and unique
alterations in tumor-associated glycosylation may also serve as a distinct feature of cancer …