[HTML][HTML] DNA methylation in the pathogenesis of type 2 diabetes in humans

C Davegårdh, S García-Calzón, K Bacos, C Ling - Molecular metabolism, 2018 - Elsevier
DNA methylation and ncRNA, respectively, in tissues from subjects with T2D and from
non-diabetic … This review will focus on a body of literature that dissects whether DNA methylation

DNA methylation in obesity and type 2 diabetes

VDF de Mello, L Pulkkinen, M Lalli… - Annals of …, 2014 - Taylor & Francis
… Altered DNA methylation has been shown … DNA methylation and consequently gene
expression. In this review we provide an overview of human studies investigating DNA methylation

The role of DNA methylation in the pathogenesis of type 2 diabetes mellitus

SAH Ahmed, SA Ansari, EPK Mensah-Brown… - Clinical …, 2020 - Springer
… Furthermore, this study found a two-fold increase in the DNA methylation of the PPARGC1A
… of PPARGC1A mRNA and PPARGC1A promoter methylation expression. In addition, the …

DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetes

T Rönn, C Ling - Epigenomics, 2015 - Taylor & Francis
… the genome-wide DNA methylation pattern in human … levels of DNA methylation in islets
from Type 2 diabetic versus … These genes include known Type 2 diabetes loci such as TCF7L2, …

DNA methylation landscapes in the pathogenesis of type 2 diabetes mellitus

Z Zhou, B Sun, X Li, C Zhu - Nutrition & metabolism, 2018 - Springer
… of type 2 diabetes mellitus (T2DM), emerging literature suggest that epigenetics, especially
DNA methylation, … Previous studies have elucidated how DNA methylation interacted with …

[HTML][HTML] DNA methylation: a cause and consequence of type 2 diabetes

M Kim - Genomics & informatics, 2019 - ncbi.nlm.nih.gov
… During the past decade, genome-wide DNA methylationDNA methylome of T2D and
discusses DNA methylation as both a cause and consequence of T2D. Therefore, DNA methylation

Programming of DNA methylation in type 2 diabetes

RA Simmons - Diabetologia, 2013 - Springer
… is between the type 2 diabetes CpG-SNPs with differential DNA methylation and islet function.
… first studies examining CpG-SNPs and DNA methylation in human islets. If these findings …

DNA methylation and type 2 diabetes: novel biomarkers for risk assessment?

GA Raciti, A Desiderio, M Longo, A Leone… - International Journal of …, 2021 - mdpi.com
… In particular, we will focus on the relevance of DNA methylation biomarkers and critically
discuss the current limitations while highlighting the potential value of these novel biomarkers in …

DNA methylation markers associated with type 2 diabetes, fasting glucose and HbA1c levels: a systematic review and replication in a case–control sample of the …

E Walaszczyk, M Luijten, AMW Spijkerman, MJ Bonder… - Diabetologia, 2018 - Springer
DNA methylation changes associated with type 2 diabetes and… methylation loci identified
in the reviewed EWASs, we also performed a replication study in blood samples of 100 diabetic

DNA methylation: an epigenetic insight into type 2 diabetes mellitus

F Alam, A Islam, S Hua Gan… - Current …, 2016 - ingentaconnect.com
… of type 2 diabetes mellitus (T2DM). Current evidences indicate an association of DNA
methylation … roles in T2DM pathogenesis and how DNA methylation interacts with these factors. …