… glutamate-cysteine ligase (GCLM) is regulated by either of two regions of the promoter; an
antioxidant response element (… AREs, one having a variant sequence. The results indicate that …

… named the antioxidant response element because it was inducible by phenolic antioxidants.
… The variant EpRE has the “core” EpRE sequence 5′-GTTACgaaGC-3′ instead of 5′-…

… the antioxidant response element (ARE), a cis-acting enhancer sequence found in the promoter
region of many genes that encode antioxidant and … Human genetic variation can have a …

… elements of phase II genes. The dynamic expression of phase II genes is regulated by the
transcriptional regulatory element called antioxidant response element (… C allelic variant had a …

… a milder CF phenotype (36), genetic variation in GCLC that leads to improved intracellular
… In conclusion, this study found an association between variants in GCLC, a novel candidate …

… antioxidants and can be produced from glutamate, cysteine and … Glutamate cysteine ligase
(GCL) is the enzyme catalyzing the … Notably, CREB3L1 (cAMP responsive element binding …

… the main endogenous antioxidants whose plasmatic concentrations were reported to be
reduced in diabetes patients [7]. GSH synthesis requires the glutamate-cysteine ligase enzyme (…

… A third extracellular variant, EcSOD or SOD3, is secreted and … and binds to the antioxidant
response element (ARE), … (GSTs), cysteine–glutamate exchange transporter, and multidrug …

… The gene of the key GSH-synthesizing enzyme, glutamate cysteine ligase modifier (GCLM)
subunit, is strongly associated with schizophrenia in two case-control studies and in one …

… (NQO1), heme oxygenase 1 (HMOX1), glutamate-cysteine ligase (GCL), and aldo-keto …
a DNA recognition sequence known as antioxidant response element (ARE) or electrophile …