Amiodarone hepatotoxicity: prevalence and clinicopathologic correlations among 104 patients
JH Lewis, RC Ranard, A Caruso, LK Jackson… - Hepatology, 1989 - journals.lww.com
… However, levels of amiodarone may persist in various tissues for weeks to months following
… any organ toxicity. Accordingly, the risks posed and benefits offered by amiodarone should …
… any organ toxicity. Accordingly, the risks posed and benefits offered by amiodarone should …
Amiodarone hepatotoxicity with absent phospholipidosis and steatosis: a case report and review of amiodarone toxicity in various organs
A Cimic, J Sirintrapun - Case reports in pathology, 2013 - Wiley Online Library
… amiodarone toxicity in the liver without phospholipidosis or steatosis. In doing so, we will review
the various effects of amiodarone toxicity in various organs… for viral hepatitis was negative…
the various effects of amiodarone toxicity in various organs… for viral hepatitis was negative…
Amiodarone hepatotoxicity
M Babatin, SS Lee, PT Pollak - Current vascular pharmacology, 2008 - ingentaconnect.com
… Amiodarone adverse effects may occur in the organs that interact with ultraviolet light (skin,
cornea), oxygen (lungs), iodine (thyroid), metabolism of exogenous compounds (liver, gut) …
cornea), oxygen (lungs), iodine (thyroid), metabolism of exogenous compounds (liver, gut) …
Histopathologic analysis of suspected amiodarone hepatotoxicity
JH Lewis, F Mullick, KG Ishak, RC Ranard, B Ragsdale… - Human pathology, 1990 - Elsevier
This analysis of the morphology of suspected amiodarone (AD) liver disease is based on a
study of liver specimens from 17 individuals. Changes similar to alcoholic liver injury were …
study of liver specimens from 17 individuals. Changes similar to alcoholic liver injury were …
Hepatotoxicity associated with amiodarone therapy
KK Flaharty, SL Chase… - … : The Journal of …, 1989 - Wiley Online Library
… a role in the development of multiple organ toxicity.' Such … amiodaroneinduced
hepatotoxi~ity.~'~ In cases of liver disease, the histopathologic pattern resembles that of alcoholic …
hepatotoxi~ity.~'~ In cases of liver disease, the histopathologic pattern resembles that of alcoholic …
Hepatotoxicity of amiodarone
JJ RUMESSEN - Acta Medica Scandinavica, 1986 - Wiley Online Library
… hepatitis with cholestasis during exposure to amiodarone and its … able that amiodarone
actually induced cholestatic hepatitis in … is the same that causes organ injury. In conclusion, solid …
actually induced cholestatic hepatitis in … is the same that causes organ injury. In conclusion, solid …
Acute hepatotoxicity of intravenous amiodarone: case report and review of the literature
CC Chen, CC Wu - American journal of therapeutics, 2016 - journals.lww.com
… and no other organ damage. Aspirin, clopidogrel, mexiletine, and isosorbide mononitrate
were used simultaneously; however, all these agents did not show obvious hepatotoxicity. …
were used simultaneously; however, all these agents did not show obvious hepatotoxicity. …
Hepatotoxicity during rapid intravenous loading with amiodarone: description of three cases and review of the literature
AER Bravo, J Drewe, RG Schlienger… - Critical care …, 2005 - journals.lww.com
… Amiodarone is associated with many adverse effects involving different organs. Although
they are generally mild, 10% to 15% of patients require withdrawal of the drug as a result of …
they are generally mild, 10% to 15% of patients require withdrawal of the drug as a result of …
Autophagy alleviates amiodarone-induced hepatotoxicity
F Wandrer, Ž Frangež, S Liebig, K John, F Vondran… - Archives of …, 2020 - Springer
… amiodarone-mediated liver toxicity, we analyzed the activation of effector caspase-3/-7 in
amiodarone-… 200 µM amiodarone (data not shown), a concentration which was found to cause …
amiodarone-… 200 µM amiodarone (data not shown), a concentration which was found to cause …
Mechanisms of hepatocellular toxicity associated with dronedarone—A comparison to amiodarone
A Felser, K Blum, PW Lindinger, J Bouitbir… - Toxicological …, 2013 - academic.oup.com
… of hepatotoxicity of dronedarone in vitro and to compare them with amiodarone. We used …
cells for 24h, dronedarone and amiodarone caused cytotoxicity and apoptosis starting at 20 …
cells for 24h, dronedarone and amiodarone caused cytotoxicity and apoptosis starting at 20 …
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