Regulation of ZEB1 function and molecular associations in tumor progression and metastasis

M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
… of ZEB1 in mediating tumor progression and metastasis and describe the ways in which protein
modifications can regulate its molecular associations and function… regulation of ZEB1′s …

RETRACTED ARTICLE: Upregulation of long noncoding RNA ZEB1-AS1 promotes tumor metastasis and predicts poor prognosis in hepatocellular carcinoma

T Li, J Xie, C Shen, D Cheng, Y Shi, Z Wu, X Deng… - Oncogene, 2016 - nature.com
ZEB1-AS1) on tumor progressionZEB1-AS1 regulates cancer metastasis by regulating
ZEB1 in vivo. Different clones were injected into the tail vein of nude mice and lung metastasis

ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance

P Zhang, Y Sun, L Ma - Cell cycle, 2015 - Taylor & Francis
… cells that have undergone EMT acquire cancer stem cell properties … that ZEB1 regulates
radioresistance in breast cancer cells … by which ZEB1 regulates tumor progression and treatment …

[HTML][HTML] ZEB1 promotes the progression and metastasis of cervical squamous cell carcinoma via the promotion of epithelial-mesenchymal transition

Y Ma, X Zheng, J Zhou, Y Zhang… - International Journal of …, 2015 - ncbi.nlm.nih.gov
… contributor to the process of malignant cancer progression. ZEB1 is encoded by the TCF8
gene … In this study, we detected ZEB1, E-cadherin, β-catenin and N-cadherin in tumors from 81 …

E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer

O Schmalhofer, S Brabletz, T Brabletz - Cancer and Metastasis Reviews, 2009 - Springer
… cells to invade the stroma and subsequently to disseminate and metastasize [199]. In this
context, ZEB1-mediated loss of the basement membrane contributes to tumor progression and …

LincRNA-ROR promotes invasion, metastasis and tumor growth in pancreatic cancer through activating ZEB1 pathway

H Zhan, Y Wang, C Li, J Xu, B Zhou, J Zhu, H Han… - Cancer letters, 2016 - Elsevier
metastasis in PC cells may partly by activation of ZEB1role of linc-ROR in iPSCs and ESCs
and other cancers, and suggest the potential important role of linc-ROR in EMT and cancer

[HTML][HTML] ZEB1: catalyst of immune escape during tumor metastasis

J Lu, F Fei, C Wu, J Mei, J Xu, P Lu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
ZEB1 expression and its role in tumor immune evasion, which may make it a promising
therapeutic target for tumor … acts as a driver of EMT and cancer progression. Aberrant expression …

[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications

Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
… for treating cancer. In this review, we outlined the biological function of ZEB1 in tumorigenic
progression and … In cancer progression, a crucial target of Wnt is the transcription factor …

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

JE Larsen, V Nathan, JK Osborne… - The Journal of …, 2016 - Am Soc Clin Investig
… cell lines and showed that ZEB1 also promoted tumor growth and metastatic capacity in vivo.
… –40) studies of ZEB1 to establish its important functional role in lung cancer development. …

Pleiotropic roles for ZEB1 in cancer

J Caramel, M Ligier, A Puisieux - Cancer research, 2018 - AACR
… to sustain primary tumor growth and to drive the seeding and establishment of metastases
at distal sites, generally represent a minor fraction of the whole cancer cell population. …